Nitric oxide negatively regulates gibberellin signaling to coordinate growth and salt tolerance in Arabidopsis  

作　　者：Lichao Chen Shuhao Sun Chun-Peng Song Jian-Min Zhou Jiayang Li Jianru Zuo 

机构地区：[1]State Key Laboratory of Plant Genomics,Institute of Genetics and Developmental Biology,Chinese Academy of Sciences,Beijing 100101,China [2]College of Advanced Agricultural Sciences,University of Chinese Academy of Sciences,Beijing 100049,China [3]CAS Center for Excellence in Molecular Plant Sciences,Chinese Academy of Sciences,Beijing 100101,China [4]State Key Laboratory of Crop Stress Adaptation and Improvement,Collaborative Innovation Center of Crop Stress Biology,Henan University,Kaifeng,Henan 475001,China [5]Hainan Yazhou Bay Seed Laboratory,Sanya,Hainan 572025,China

出　　处：《Journal of Genetics and Genomics》2022年第8期756-765,共10页遗传学报（英文版）

基　　金：supported by grants from the National Natural Science Foundation of China (31830017 and 31521001);Chinese Academy of Sciences (XDB27030207);State Key Laboratory of Plant Genomics (SKLPG2020-22)

摘　　要：In response to dynamically altered environments,plants must finely coordinate the balance between growth and stress responses for their survival.However,the underpinning regulatory mechanisms remain largely elusive.The phytohormone gibberellin promotes growth via a derepression mechanism by proteasomal degradation of the DELLA transcription repressors.Conversely,the stress-induced burst of nitric oxide(NO)enhances stress tolerance,largely relying on NO-mediated S-nitrosylation,a redox-based posttranslational modification.Here,we show that S-nitrosylation of Cys-374 in the Arabidopsis RGA protein,a key member of DELLAs,inhibits its interaction with the F-box protein SLY1,thereby preventing its proteasomal degradation under salinity condition.The accumulation of RGA consequently retards growth but enhances salt tolerance.We propose that NO negatively regulates gibberellin signaling via S-nitrosylation of RGA to coordinate the balance of growth and stress responses when challenged by adverse environments.

关 键 词：GIBBERELLIN Nitric oxide S-NITROSYLATION DELLA repressors Stress responses 

分 类 号：Q945[生物学—植物学]