Ligand-Enabled Ni-Catalyzed Enantioselective Hydroarylation of Styrenes and 1,3-Dienes with Arylboronic Acids  

作　　者：Xin-Yang Lv Chao Fan Li-Jun Xiao Jian-Hua Xie Qi-Lin Zhou 

机构地区：[1]State Key Laboratory and Institute of Elemento-Organic Chemistry,College of Chemistry,Nankai University,Tianjin 300071,China

出　　处：《CCS Chemistry》2019年第4期328-334,共7页中国化学会会刊（英文）

基　　金：The authors thank the National Natural Science Founda-tion of China(Grant#s.21790332 and 21532003);the“111”project(Grant#B06005)of the Ministry of Educa-tion of China for their financial support.

摘　　要：We report an enantioselective hydroarylation reaction of styrenes and 1,3-dienes with arylboronic acids catalyzed by nickel complexes bearing chiral spiro amino phosphine ligands.The reaction serves as an efficient,straightf orward,and mild method for the preparation of enantio enriched 1,1-diarylalkanes,which are important building blocks for the synthesis of many biologically active molecules.This redox neutral reaction uses only catalytic amounts of the reagents and is,therefore,atom economical and environmentally benign.

关 键 词：nickel catalyst enantioselective hydroarylation ALKENE ORGANOBORON chiral spiro aminophosphine 

分 类 号：O62[理学—有机化学]