Pharmacotherapy of Diabetes Mellitus Type 2: A Review on Various Hypoglycemics  

作　　者：Muhammad Khalid Khan Rizwan U Baig 

机构地区：[1]Drug Delivery and Cosmetics Lab(DDCL),Faculty of Pharmacy,Gomal University,Dera Ismail Khan29050,Pakistan [2]Department of Pharmacy,Quaid-i-Azam University Islamabad,Islamabad 44000,Pakistan

出　　处：《Journal of Clinical and Nursing Research》2022年第5期57-67,共11页临床护理研究（英文）

摘　　要：Diabetes is a cosmopolitan medical issue ramifying a large population regardless of ethnicity.Elevated glycemic condition in a patient is explained as diabetes.It can be mainly categorized into Non-Insulin Dependent Diabetes Mellitus(NIDDM)and Insulin Dependent Diabetes Mellitus(IDDM)or Type 1 or Type 2 respectively.Type 1 or IDDM needs insulin therapy exclusively while Type 2 can be controlled via various hypoglycemic agents.Conventional classes contain glitazones,biguanides,sulfonylurea’s and soon,while newly developed drug classes include gliptins or DPP-4 inhibitors,SGLT-2 receptor inhibitors and GLP-1 receptor agonists.The novelty in the anti-hyperglycemic agents have given promising results as compared to the conventional drugs.Insulin cannot be negated as far as its glycemic control is concerned.Furthermore,development of Insulin analogues like detemir,glargine,Lisprohave been shown to control glucose levels in the plasma more efficiently.

关 键 词：Pre-prandial POSTPRANDIAL KETOACIDOSIS ADIPOGENESIS Oral Hypoglycemic Drugs(OHD) 

分 类 号：R58[医药卫生—内分泌]