雅博司对早期肝性脑病患者的临床意义  

The Clinical Significance of Ornithine Aspartatelnjection in Patients with Early Hepatic Encephalopathy

作　　者：刘君 LIU Jun(Intensive Care Unit,Dalian Sixth People's Hospital,Dalian 116000,China)

机构地区：[1]大连市第六人民医院重症监护室,辽宁大连116000

出　　处：《中国医药指南》2022年第27期100-102,共3页Guide of China Medicine

摘　　要：目的 探讨雅博司对早期肝性脑病患者的临床意义分析。方法 选取2018年3月至2020年3月在大连市第六人民医院重症监护室的40例早期肝性脑病患者,随机分为试验组(n=20)和对照组(n=20)。对两组早期肝性脑病患者均采用临床传统治疗,对照组20例早期肝性脑病患者在此基础上给予常规抗肝昏迷治疗等药物临床治疗;试验组20例早期肝性脑病患者在此基础上采取雅博司进行临床治疗,比较两组早期肝性脑病患者治疗后烦躁恢复人数,计算力恢复人数和扑翼样震颤恢复人数,昏迷恢复人数。比较两组早期肝性脑病患者病情发展评分,症状评分,肝性脑病分级评分。结果 试验组早期肝性脑病患者治疗后烦躁恢复人数,计算力恢复人数和扑翼样震颤恢复人数,昏迷恢复人数多于对照组早期肝性脑病患者(P <0.05)。试验组早期肝性脑病患者病情发展评分,症状评分,肝性脑病分级评分优于对照组早期肝性脑病患者(P <0.05)。结论 对早期肝性脑病患者来说,采取雅博司治疗的临床效果较好,可以有效改善早期肝性脑病患者临床治疗效果,值得推广。Objective To explore the clinical significance of ornithine aspartatelnjectioni in patients with early hepatic encephalopathy.Methods Forty patients with early hepatic encephalopathy in the intensive care unit of Dalian Sixth People’s Hospital from March 2018 to March 2020 were randomly divided into experimental group and control group. The patients with early hepatic encephalopathy in the two groups were treated with traditional clinical treatment, and 20 patients with early hepatic encephalopathy in the control group were treated with routine anti hepatic coma treatment and other drugs;On this basis, 20 patients with early hepatic encephalopathy in the experimental group were treated with ornithine aspartatelnjection. The number of irritability recovery, computational power recovery, flapping wing tremor recovery and coma recovery in the two groups were compared. The disease development score, symptom score and grade score of hepatic encephalopathy were compared between the two groups. Results The number of patients with early hepatic encephalopathy in the experimental group recovered from irritability,computational power, flapping wing tremor and coma after treatment was significantly higher than that in the control group(P<0.05). The development score, symptom score and grade score of hepatic encephalopathy in the experimental group were better than those in the control group(P<0.05). Conclusion For patients with early hepatic encephalopathy, the clinical effect of ornithine aspartatelnjection treatment is better, which can effectively improve the clinical treatment effect of patients with early hepatic encephalopathy, which is worthy of promotion.

关 键 词：早期肝性脑病 雅博司 临床有效性 

分 类 号：R742[医药卫生—神经病学与精神病学]