Efficacy and safety of a cream containing octyl salicylic acid,salicylic acid,linoleic acid,nicotinamide,and piroctone olamine combined with 5%benzoyl peroxide in the treatment of acne vulgaris:a randomized controlled study  

作　　者：Wei Li Qian Yu Zhong Shen Lanxin Zhang Wei Zhang Caixia Li 

机构地区：[1]Department of Medical Cosmetology,Shanghai Dermatology Hospital,Tongji University School of Medicine,Shanghai 200443,China [2]Department of Medical Mycology,Shanghai Dermatology Hospital,Tongji University School of Medicine,Shanghai 200443,China [3]Loreal China Co.,Ltd,Shanghai 200040,China.

出　　处：《Chinese Medical Journal》2022年第11期1381-1382,共2页中华医学杂志（英文版）

基　　金：Science and Technology Commission of Shanghai Municipality(No. 20Y11905600);Shanghai Municipal Health Commission(No. 20194Y0337)

摘　　要：To The Editor:Acne vulgaris is a chronic inflammatory skin disease involving the sebaceous glands.It has an incidence of approximately 9.4%,often occurring in adolescents.[1]The disease itself and the scars left after treatment can cause psychological stress in adolescents and seriously affect patients’quality of life.[2]At present,skin care products,either alone or in combination with medical drugs,have become important means for treating acne.This single-center,single-blind(clinician-blind),masculine-paralleled,randomized study(Registration number:ChiCTR2100051398)evaluated the efficacy and safety of a cream containing octyl salicylic acid,salicylic acid,linoleic acid,nicotinamide,and piroctone olamine(Duo+,La Roche-Posay,Paris,France)alone and in combination with benzoyl peroxide(BPO,Galderma,Paris,France)for the treatment of mild-to-moderate acne.The research was approved by the Ethics Committee of Shanghai Skin Disease Hospital,China(No.2020-13 ke).All participants provided written informed consent.

关 键 词：BENZOYL PEROXIDE TREATMENT 

分 类 号：R758.733[医药卫生—皮肤病学与性病学]