Impact of gamete health on fertilization and embryo development: An overview  

作　　者：Chorya Jaypalsinh B Sutaria Tarunkumar V Chaudhari Ravjibhai K Chaudhari Chandrakant F 

机构地区：[1]Department of Gynaecology and Obstetrics,College of Veterinary Science and Animal Husbandry,Kamdhenu University,Sardarkrushinagar,Gujarat,India

出　　处：《Asian pacific Journal of Reproduction》2022年第5期201-207,共7页亚太生殖杂志（英文版）

摘　　要：A genetically and functionally proficient gamete is essential for normal fertilization and embryonic development.Any change in gamete health affects fertilization and subsequent events,including embryonic development,implantation,and successful pregnancy.This present review focuses on the role of gamete health on fertilization and embryo development.Several conventional and advanced methods are used to evaluate the morphology and functions of gametes.The abnormal spermatozoa adversely affect fertilization events,which results in reduced cleavage/blastocyst/implantation and pregnancy rate during assisted reproductive techniques.Poor oocyte quality is also one of the reasons for infertility,although the oocyte has an innate capacity to repair a certain amount of abnormality of both oocyte and spermatozoa.Therefore,oocyte health carries more responsibilities during fertilization events.The gamete,either spermatozoa or oocyte,should have optimum morphological and functional health to fertilize and develop a competent embryo successfully.Thus,it is of prime importance to consider the gamete health parameters while dealing with infertility.

关 键 词：EMBRYO FERTILIZATION GAMETE OOCYTE SPERM 

分 类 号：R329.2[医药卫生—人体解剖和组织胚胎学]