基于因子分析的128例胃食管反流性咳嗽患者中医证素特点研究  

Characteristics of TCM Syndromes in 128 Cases of Gastroesophageal Reflux-related Cough Based on Factor Analysis

作　　者：郭淑娟 史利卿[2] 季坤[2] 马建岭[2] 董尚娟 李扭扭[2] 白逸晨 王亚杰 GUO Shujuan;SHI Liqing;JI Kun;MA Jianling;DONG Shangjuan;LI Niuniu;BAI Yichen;WANG Yajie(Beijing University of Chinese Medicine,Beijing 100029,China;Dongfang Hospital,Beijing University of Chinese Medicine,Beijing 100078,China)

机构地区：[1]北京中医药大学,北京100029 [2]北京中医药大学东方医院,北京100078

出　　处：《辽宁中医杂志》2022年第8期17-20,共4页Liaoning Journal of Traditional Chinese Medicine

基　　金：国家自然科学基金(81373588);北京市自然科学基金面上项目(7192115);北京市自然科学基金青年项目(7184224);中央高校基本科研业务费专项项目(2018-JYBZZ-JS103,2019-JYB-JS-092)。

摘　　要：目的探讨胃食管反流性咳嗽患者的中医证素分布特点。方法从东方医院呼吸热病科咳嗽专病数据库中提取2009年1月—2020年1月就诊的128例胃食管反流性咳嗽患者的中医证候资料及一般资料,采用二分类法处理中医四诊信息,运用因子分析提取病性证素与病位证素,归纳患者的中医证素分布情况。结果因子分析共提取9个公因子,累计贡献率达到67.22%。在128例GERC中,病位证素主要为胃(60.16%,77/128)、脾(44.53%,57/128)、肺(35.94%,46/128)、肝(34.38%,44/128);病性证素主要为湿热(53.13%,68/128)、郁热(32.02%,41/128)、气滞(26.56%,34/128)、痰湿(21.88%,28/128)、阳虚(15.63%,20/128)、风邪(9.38%,12/128)。结论胃食管反流性咳嗽的病位证素主要在胃,涉及到脾、肺、肝;病性涉及湿热、郁热、气滞、痰湿、阳虚、风邪等,以上病性要素可独立存在,亦可相兼互见,多为虚实夹杂、寒热错杂,临床需加以详辨。Objective To analyze the distribution characteristics of TCM syndromes in gastroesophageal reflux-related cough(GERC).Methods The clinical symptoms and tongue and pulse information of 128 patients with GERC were collected.The collected data was processed using a binary taxonomy,and then was analyzed through factor analysis.On the basis of the above data,the characteristics and distribution of TCM syndromes were analyzed.Results There were 9 factors extracted by factor analysis,contributing 67.22%of the total variance.From the highest to the lowest,the syndrome factors of location were stomach(60.16%,77/128),spleen(44.53%,57/128),lung(35.94%,46/128)and liver(34.38%).The syndrome factors of the pathogenesis were damp-heat(53.13%),stagnant heat(32.02%,41/128),Qi stagnation(26.56%,34/128),phlegm(21.88%,28/128),Yang deficiency(15.63%,20/128)and wind(9.38%,12/128).Conclusion GERC is mainly located in the stomach,involving in spleen,lung and liver.The syndrome factors of the pathogenesis include damp-heat,stagnant heat,Qi stagnation,phlegm,Yang deficiency and wind.The above disease elements can exist independently or can be seen at the same time.Most of them are mixed with deficiency and excess,mixed with cold and heat,and need to be discussed in detail in clinical practice.

关 键 词：胃食管反流性咳嗽 病性证素 病位证素 因子分析 

分 类 号：R571[医药卫生—消化系统]