脑梗死后患者认知功能障碍发病机制及中医治疗研究进展  

The occurrence mechanism of post stroke cognitive impairment and the research progress of TCM treatment

作　　者：乔春梅 瞿迁 方铁根 李成年 QIAO Chunmei;QU Qian;FANG Tiegen;LI Chengnian(Clinical Department,Hubei University of Traditional Chinese Medicine,Wuhan 430065,China)

机构地区：[1]湖北中医药大学中医临床学院,湖北武汉430065

出　　处：《陕西中医》2022年第10期1487-1488,F0003,共3页Shaanxi Journal of Traditional Chinese Medicine

基　　金：湖北省教育科学“十二五”规划项目(2014B097);中医药古籍文献和特色技术传承专项(GZY-KJS-2020-068)。

摘　　要：缺血性脑卒中,俗称脑梗死,是血管闭塞导致机体局部缺血引起的病变。约20%~30%的脑梗死患者合并认知功能障碍,脑梗死后认知功能障碍(PSCI)患者的生活质量及生存时间受到严重影响,需及时治疗。目前,PSCI的发病机制尚未完全明确,其与大脑认知功能神经环路、神经递质分泌紊乱、炎症因子与氧自由基受损等相关。PSCI危险因素有高血压、高血脂、高血糖、心房颤动、吸烟等。中医治疗PSCI有独特优势,包括中药汤剂、综合康复治疗、针灸等治疗方法,可提高治疗总有效率,缩短患者的住院时间,修复认知功能,提升患者满意度和生活质量,对PSCI患者的康复具有重要意义。Ischemic stroke,commonly known as cerebral infarction,is a lesion caused by ischemia caused by vascular occlusion.About 20%~30%of patients with cerebral infarction are complicated with cognitive dysfunction,and the quality of life and survival time of post stroke cognitive impairment(PSCI)patients are seriously affected,requiring timely treatment.At present,the pathogenesis of PSCI has not been fully clarified,which is related to the neural circuit of brain cognitive function,neurotransmitter secretion disorder,inflammatory factors and oxygen free radical damage.Risk factors for PSCI include hypertension,hyperlipidemia,hyperglycemia,atrial fibrillation,smoking,etc.TCM treatment of PSCI has unique advantages,including TCM decoction,comprehensive rehabilitation treatment,acupuncture and other treatment methods,which can improve the total effective rate,shorten the length of hospital stay of patients,repair cognitive function,improve patient satisfaction and quality of life,which is great significance to the rehabilitation of PSCI patients.

关 键 词：脑梗死 认知功能障碍 中医治疗 发病机制 危险因素 

分 类 号：R743.31[医药卫生—神经病学与精神病学]