Syndecan-1在乳腺癌中的作用及研究进展  

The role and research progress of Syndecan-1 in breast cancer

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作  者:庄海姣 王英杰 倪志新 赵松[1] ZHUANG Haijiao;WANG Yingjie;NI Zhixin;ZHAO Song(Department of Breast Surgery,The First Afiliated Hospilal of Harbin Medical University,Harbin 150001,P.R.China)

机构地区:[1]哈尔滨医科大学附属第一医院乳腺外科,哈尔滨150001

出  处:《中国普外基础与临床杂志》2022年第9期1256-1260,共5页Chinese Journal of Bases and Clinics In General Surgery

摘  要:目的 对Syndecan-1在乳腺癌中的作用及研究进展的相关成果进行系统性综述,以期为乳腺癌的治疗及预后研究提供方向。方法 通过检索近年来相关文献,分析和总结Syndecan-1在乳腺癌中的独特性质及作用。结果 Syndecan-1在乳腺癌的诊断和治疗中具有重要意义并可作为乳腺癌潜在的预后标志物,其亦可以作为乳腺癌潜在的治疗靶点,对乳腺癌的临床应用具有重大研究价值。结论 Syndecan-1以其独特的性质及作用在乳腺癌的发生发展以及治疗预后方面上具有重大研究价值,可指向性地应用于乳腺癌研究领域。Objective The results related to the role and research progress of Syndecan-1 in breast cancer are systematically reviewed, with the aim of providing new directions for the treatment and prognosis of breast cancer research. Method The unique properties and role of Syndecan-1 in breast cancer patients were analyzed and summarized by searching the relevant literatures in recent years. Results Syndecan-1 was of great significance in the diagnosis and treatment of breast cancer and could be used as a potential prognostic marker of breast cancer. Meanwhile,it could also be used as a potential therapeutic target for breast cancer, which had significant research value for clinical applications. Conclusion Syndecan-1 has been applied in the field of breast cancer research because of its unique properties and effects on the development, treatment and prognosis of breast cancer.

关 键 词:乳腺癌 SYNDECAN-1 蛋白多糖 研究进展 

分 类 号:R737.9[医药卫生—肿瘤]

 

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