快速定量相位对比法在诊断下腔静脉阻塞布加综合征中的应用价值研究  

The Application of Rapid Quantitative Phase Contrast in the Diagnosis of Inferior Vena Cava Occlusion Budd Chia Syndrome

作　　者：郑信德 杨春 路欣 周琳夕 张利军 ZHENG Xin-de;YANG Chun;LU Xin;ZHOU Lin-xi;ZHANG Li-jun(Department of Radiology,Zhongshan Hospital,Fudan University,Shanghai 200032,China;Department of Radiology,Affiliated Hospital of Xuzhou Medical University,Xuzhou 221000,Jiangsu Province,China)

机构地区：[1]上海复旦大学附属中山医院放射科,上海200032 [2]徐州医科大学附属医院放射科,江苏徐州221000

出　　处：《中国CT和MRI杂志》2022年第10期74-76,共3页Chinese Journal of CT and MRI

摘　　要：目的应用快速定量相位对比法(PC)研究下腔静脉阻塞的布加综合征(BCS),并与磁共振静脉成像(MRV)的定性指标进行比较,探讨PC定量值在诊断下腔静脉BCS中的临床应用价值。方法35例DSA确诊的下腔静脉阻塞BCS行快速定量相位对比法及MRV检查,获取PC定量值及MRV定性值;另选取35例体检发现的肝脏局灶性病灶的患者作为对照组,亦行快速定量相位对比法及MRV检查。结果PC法的定量参数(搏出量,顺向流量,平均流量,平均速度,峰值速度)诊断IVC阻塞BCS的受试者工作曲线下面积分别为0.7767,0.7788,0.7665,0.9159,及0.8947。平均速度诊断IVC阻塞BCS的敏感性、特异性及准确率分别为88.57%,85.71%及87.14%。对于IVC阻塞BCS的诊断效能,平均速度(PC法的一种定量指标)与MRV比较,两种方法C无统计学差异(P=0.0768)。结论PC法定量值可用于IVC阻塞BCS的诊断,并可提供IV阻塞BCS的血流动力学信息。Objective The purpose of this study was to analyze inferior vena cava(IVC)obstruction in Budd-Chiari syndrome(BCS)using rapid quantitative phase-contrast(PC)magnetic resonance(MR)imaging and compare the diagnostic efficacy of PC and MR venography(MRV)to explore the clinical prospects of applying PC quantitative diagnosis in IVC obstruction in BCS.Methods PC quantitative data and MRV qualitative data obtained in 35 DSA-recognized inferior vena cava obstruction BCS patients and 35 patients with liver focal lesions found in physical examination were analyzed and compared.Results The areas under the ROC curve for diagnostic parameters related to PC quantitative parameters,including stroke volume,forward flow volume,mean flux,mean velocity(MV),and peak velocity,were 0.7767,0.7788,0.7665,0.9159,and 0.8947,respectively.The sensitivity,specificity and accuracy of MV in the diagnosis of IVC obstruction were 88.57%,85.71%and 87.14%,respectively.For IVC obstruction in BCS,there was no significant difference between the diagnostic efficacy of MV(one of the quantitative parameters of PC)and that of MRV(P=0.0768).Conclusion PC can be used to diagnose IVC obstruction BCS and improving understanding hemodynamics of IVC obstruction BCS.

关 键 词：布加综合征 下腔静脉 磁共振成像 相位对比法 血液动力学 

分 类 号：R-33[医药卫生]