下肢原发性骨淋巴瘤 99 Tc m -MDP三相骨联合SPECT/CT显像1例并文献复习  

A Case Report of 99 Tc m-MDP Three-Phase Bone+SPECT/CT Imagingwith Primary Lymphoma of Bone and Relevant Literature Review

作　　者：石雪[1] 熊晓亮[1] 郝婷婷[1] 赵银龙[1] SHI Xue;XIONG Xiaoliang;HAO Tingting;ZHAO Yinlong(Department of Nuclear Medicine,Second Hospital of Jilin University,Changchun 130041,China)

机构地区：[1]吉林大学第二医院核医学科,吉林长春130041

出　　处：《标记免疫分析与临床》2022年第8期1336-1338,1347,共4页Labeled Immunoassays and Clinical Medicine

基　　金：吉林省自然科学基金(编号:20180101101JC);吉林省财政厅卫生专项项目(编号:3D518V613429);吉林省医疗卫生人才专项(编号:2019SCZT026)。

摘　　要：目的通过1例发生于双下肢骨淋巴瘤影像的回顾性分析及骨淋巴瘤相关文献复习,总结淋巴瘤影像特征,旨在加深核医学医生对骨淋巴瘤的认识,避免漏诊及误诊。方法报道1例经病理确诊为弥漫大B细胞淋巴瘤,但临床资料及部分影像特征极容易误诊骨髓炎的病例,结合相关文献,探讨骨淋巴瘤的三相骨联合SPECT/CT显像的影像学特征,及其与骨髓炎的鉴别诊断。结果通过三相骨联合SPECT/CT显像能够更全面的评估受累骨骼,降低漏诊及误诊率。结论三相骨联合SPECT/CT显像不仅能够明确病灶血供、软组织充血及骨代谢情况,同时能够通过CT显示其解剖结构的变化,与常规X线、CT及MR影像学检查相比,对骨淋巴瘤的诊断与鉴别可以提供更多的信息。Objective There are few reports on radionuclide imaging of lymphoma of bone in the field.Nuclear medicine clinicians are inexperienced.In this paper,we retrospectively analyzed the imaging of a case of lymphoma of bone occurred in both lower limbs and reviewed related literatures on lymphoma of bone.We then summarized imaging features of lymphoma.The goal of this study is to deepen the understanding of nuclear medicine clinicians on bone lymphoma and avoid missing diagnosis and mis-diagnosis.Methods A case of diffuse large B-cell lymphoma diagnosed by pathology was reported.The clinical data and some imaging features could easily be misdiagnosed as osteomyelitis.Combined with relevant literatures,we tried to explore the imaging features of three-phase bone combined with SPECT/CT imaging in lymphoma of bone and distinguish it from osteomyelitis.Results Three-phase bone combined with SPECT/CT imaging could be used to evaluate the involved bones more comprehensively,and to reduce the rate of missing diagnosis and mis-diagnosis.Conclusion Three-phase bone combined with SPECT/CT imaging can not only clarify the blood supply,soft tissue congestion and bone metabolism of the lesions,but also can display changes of its anatomical structure by CT.Compared with conventional X-ray,CT and MR imaging,it can provide more information on the diagnosis and differentiation of lymphoma of bone.

关 键 词：淋巴瘤 骨肿瘤 三相骨显像 SPECT/CT 

分 类 号：R733.4[医药卫生—肿瘤] R738.1[医药卫生—临床医学]