脾脏炎性假瘤样滤泡树突状细胞肉瘤1例报告并文献复习  

Inflammatory pseudotumor-like follicular dendritic cell sarcoma of the spleen:a case report and literature review

作　　者：杨凯铌 陈炜[1] YANG Kaini;CHEN Wei(Department of Biliary-Pancreatic Surgery,Renji Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200127,China)

机构地区：[1]上海交通大学医学院附属仁济医院胆胰外科,上海200127

出　　处：《上海医药》2022年第19期3-6,27,共5页Shanghai Medical & Pharmaceutical Journal

摘　　要：炎性假瘤样滤泡树突状细胞肉瘤(inflammatory pseudotumor-like follicular dendritic cell sarcoma,IPT-FDCS)是一种非常罕见的肿瘤,恶性程度较低,大多发生于肝脏和脾脏。本文报告1例与Epstein-Barr病毒相关的IPT-FDCS患者的诊治情况,并结合文献分析认为脾脏IPT-FDCS的发病可能与Epstein-Barr病毒感染和免疫球蛋白G相关性疾病相关。目前,脾脏IPT-FDCS的诊断主要依赖于显微镜下的形态学和免疫组织化学染色检查,首选治疗方案是根治性脾脏切除术,患者预后较好。Inflammatory pseudotumor-like follicular dendritic cell sarcoma(IPT-FDCS) is an extremely rare neoplasm with a low degree of malignancy.Most of IPT-FDCS currently reported occur in the liver and spleen.In this paper,the diagnosis and treatment of a patient with IPT-FDCS associated with Epstein-Barr virus(EBV) is reported and its pathogenesis may be related to EBV infection and immunoglobulin G-related diseases by combining with the previous literatures.The diagnosis mainly depends on microscopic morphological examination and immunohistochemical staining detection,and radical splenectomy is the most effective treatment modality and its prognosis is good.

关 键 词：脾脏肿瘤 炎性假瘤样滤泡树突状细胞肉瘤 诊断 EPSTEIN-BARR病毒 

分 类 号：R733.4[医药卫生—肿瘤] R730.4[医药卫生—临床医学]