微创腹腔镜子宫肌瘤剔除术与传统开腹手术治疗子宫肌瘤的临床价值分析  

Clinical value analysis of minimally invasive laparoscopic myomectomy and conventional open surgery in the treatment of uterine fibroids

作　　者：宋新玲 SONG Xin-ling(Panjin Central Hospital,Panjin 124010,China)

机构地区：[1]辽宁省盘锦市中心医院,124010

出　　处：《中国实用医药》2022年第20期71-73,共3页China Practical Medicine

摘　　要：目的分析微创腹腔镜子宫肌瘤剔除术与传统开腹手术治疗子宫肌瘤的临床疗效。方法80例子宫肌瘤患者,随机分为对照组和观察组,各40例。对照组患者实施传统开腹手术治疗,观察组应用微创腹腔镜子宫肌瘤剔除术治疗。比较两组临床恢复指标(术后下地活动时间、胃肠道排气时间、总住院时间)、并发症发生情况及手术前后痛觉应激生化指标(白细胞介素-6、细胞P物质、前列腺素E_(2))、卵巢功能指标[促黄体生成素(LH)、促卵泡生成激素(FSH)、雌二醇(E_(2))]。结果观察组术后下地活动时间(16.24±1.41)h、胃肠道排气时间(16.24±1.41)h、总住院时间(6.56±0.21)d均短于对照组的(18.40±2.21)h、(19.40±2.23)h、(8.21±1.21)d,差异具有统计学意义(P<0.05)。术前,两组白细胞介素-6、细胞P物质、前列腺素E_(2)、LH、FSH、E_(2)水平比较,差异无统计学意义(P>0.05);术后,观察组白细胞介素-6(6.56±0.81)pg/ml、细胞P物质(5.43±0.72)μg/ml、前列腺素E_(2)(131.10±16.12)μg/ml、LH(18.56±2.25)U/L、FSH(20.56±2.25)U/L均低于对照组的(8.86±0.92)pg/ml、(7.21±0.72)μg/ml、(181.12±24.21)μg/ml、(22.51±4.02)U/L、(23.44±2.61)U/L,E_(2)(241.19±13.32)pmol/L高于对照组的(221.19±10.10)pmol/L,差异具有统计学意义(P<0.05)。观察组并发症发生率为5.00%(2/40),低于对照组的20.00%(8/40),差异具有统计学意义(P<0.05)。结论子宫肌瘤患者应用微创腹腔镜子宫肌瘤剔除术治疗并发症少,可减轻痛觉应激,加速临床恢复,维持卵巢功能,值得推广。Objective To analyze the clinical efficacy of minimally invasive laparoscopic myomectomy and conventional open surgery in the treatment of uterine fibroids.Methods A total of 80 patients with uterine fibroids were randomly divided into control group and observation group,with 40 cases in each group.Patients in the control group were treated with conventional open surgery,and patients in the observation group were treated with minimally invasive laparoscopic myomectomy.Both groups were compared in terms of clinical recovery indicators(postoperative off-bed activity time,gastrointestinal exhaust time,total hospitalization time),complications and biochemical indicators of pain stress(interleukin-6,cellular substance P,prostaglandin E_(2)),ovarian function indicators[luteinizing hormone(LH),follicle-stimulating hormone(FSH),estradiol(E_(2))]before and after surgery.Results The postoperative off-bed activity time(16.24±1.41)h,gastrointestinal exhaust time(16.24±1.41)h,and total hospitalization time(6.56±0.21)d in the observation group were all shorter than(18.40±2.21)h,(19.40±2.23)h,and(8.21±1.21)d in the control group,and the differences were statistically significant(P<0.05).Before surgery,there was no statistically significant difference in the levels of interleukin-6,cellular substance P,prostaglandin E_(2),LH,FSH,and E_(2) between the two groups(P>0.05).After surgery,the interleukin-6(6.56±0.81)pg/ml,cellular substance P(5.43±0.72)μg/ml,prostaglandin E_(2)(131.10±16.12)μg/ml,LH(18.56±2.25)U/L,FSH(20.56±2.25)U/L in the observation group were lower than(8.86±0.92)pg/ml,(7.21±0.72)μg/ml,(181.12±24.21)μg/ml,(22.51±4.02)U/L,(23.44±2.61)U/L in the control group;the E_(2)(241.19±13.32)pmol/L in the observation group was higher than(221.19±10.10)pmol/L in the control group;all the differences were statistically significant(P<0.05).The incidence of complications in the observation group was 5.00%(2/40),which was lower than 20.00%(8/40)in the control group,and the difference was statistically signific

关 键 词：腹腔镜 子宫肌瘤剔除术 子宫肌瘤 卵巢功能 

分 类 号：R737.33[医药卫生—肿瘤]