咽鼓管球囊扩张术治疗鼻咽癌放疗后咽鼓管功能障碍的效果观察  

Efficacy of balloon dilation of the eustachian tube in the treatment of eustachian tube dysfunction after radiotherapy for nasopharyngeal carcinoma

作　　者：汪洋[1] 聂红玉 李小英 WANG Yang;NIE Hong-yu;LI Xiao-ying(Department Otolaryngology,Huangmei County People's Hospital/Huangmei Campus,Zhongnan Hospital of Wuhan University,Huanggang 435500,China)

机构地区：[1]湖北省黄梅县人民医院/武汉大学中南医院黄梅医院耳鼻喉科,黄冈435500

出　　处：《中国肿瘤临床与康复》2022年第8期910-913,共4页Chinese Journal of Clinical Oncology and Rehabilitation

摘　　要：目的 探讨咽鼓管球囊扩张术(BDET)治疗鼻咽癌放疗后咽鼓管功能障碍(ETD)的临床效果。方法 选取2017年1月至2019年6月间黄梅县人民医院收治的62例手术治疗的鼻咽癌放疗后ETD患者,按照随机数字表法分为观察组和对照组,每组31例。对照组患者采用鼓膜置管术治疗,观察组患者采用BDET治疗,比较两组患者的临床效果、视觉模拟评分及咽鼓管功能障碍评分。结果 术后12个月,两组患者气导听阈、平均气骨导差和鼓室压图比较,差异均有统计学意义(均P<0.05)。观察组患者手术治疗总有效率为83.9%,高于对照组的51.6%,差异有统计学意义(P<0.05)。术后12个月时,两组患者耳闷、听觉模糊、耳痛及耳鸣评分均降低,且观察组均低于对照组,差异均有统计学意义(均P<0.05)。术后12个月时,两组患者咽鼓管功能障碍评分均降低,且观察组低于对照组,差异均有统计学意义(均P<0.05)。结论 BDET治疗鼻咽癌放疗后ETD,可有效改善患者的气导听阈、平均气骨导差、鼓室压图及咽鼓管测压,提高术后VAS和咽鼓管功能障碍评分,治疗总有效率优于鼓膜置管术。Objective To analyze the effects of balloon dilation of the eustachian tube(BDET) in the treatment of eustachian tube dysfunction(ETD) after radiotherapy for nasopharyngeal. Methods Sixty-two patients with ETD who underwent surgical treatment and radiotherapy for nasopharyngeal carcinoma were selected at Huangmei County People’s Hospital between January 2017 and June 2019. They were divided into an observation group and a control group using random table method with 31 patients in each group. The observation group underwent BDET and the control group underwent grommet insertion. Clinical efficacy, the visual analogue scale(VAS) scores and the eustachian tube dysfunction questionnaire(ETDQ-7) scores were compared between the two groups. Results At 12 months after the operation, there was no significant differences in air conduction hearing threshold, mean air-bone gap and tympanogram between the two groups(P<0.05). The overall efficacy rate was 83.9% in the observation group which was significantly higher than 51.6% of the control group(P<0.05). At 12 months after the operation, the scores of ear stuffiness, blurred hearing, earache, and tinnitus were significantly reduced in the two groups(P<0.05), and the scores were significantly lower in the observation group than in the control group(all P<0.05). At 12 months after the operation, the ETDQ-7 scores decreased in the two groups with the observation group were significantly lower than the control group(all P<0.05). Conclusion BDET after radiotherapy for nasopharyngeal carcinoma can effectively improve air conduction hearing threshold, mean air-bone gap, tympanogram and tubomanometry for the treatment of ETD. Meanwhile, it can improve postoperative VAS and ETDQ-7 scores, and the overall efficacy rate is superior to tympanostomy tube insertion.

关 键 词：鼻咽肿瘤 咽鼓管功能障碍 咽鼓管球囊扩张术 

分 类 号：R739.6[医药卫生—肿瘤]