四十岁以上居民糖尿病流行病学调查和肿瘤发病风险相关性研究  

Results from epidemiologic investigation of diabetes in residents over 40 years old and the association with cancer risk

作　　者：陈静[1] 刘伟平 刘茹 CHEN Jing;LIU Wei-ping;LIU Ru(Department of Renal Endocrinology,Second Affiliated Hospital of Xi'an Medical College,Xi'an 710038,China;Department of Cardiology,Second Affiliated Hospital of Xi'an Medical College,Xi'an 710038,China)

机构地区：[1]西安医学院第二附属医院肾脏内分泌科,西安710038 [2]西安医学院第二附属医院心血管内科,西安710038

出　　处：《中国肿瘤临床与康复》2022年第8期941-944,共4页Chinese Journal of Clinical Oncology and Rehabilitation

摘　　要：目的 探讨四十岁以上居民糖尿病流行病学调查和肿瘤发病风险的相关性。方法 选取2021年1月至2021年9月间西安市某三甲医院近两年来收治的40岁以上9 880名调查对象,其中糖尿病患者1 388例,采用问卷调查、体格检查和抽血化验的方式,分析糖尿病流行病学调查和肿瘤发病风险的相关性。结果 糖尿病组患者腰臀比、性别、年龄与血糖之间存在正相关关系,是危险因素。工作与糖尿病患病存在负相关,是保护性因素,退休、家族史与糖尿病患病存在正相关,是危险因素。咖啡、豆制品、水果、鲜榨果蔬汁、跳舞是保护性因素,可降低糖尿病发生风险,油炸食品、打鼾增加是糖尿病发生的危险性因素。9 880名调查对象中,肿瘤患者159例,其中乳腺癌40例,子宫内膜癌22例,结直肠癌11例。糖尿病患者肿瘤患病率为4.0%(56例),高于非糖尿病组患者的1.2%(103例),差异有统计学意义(P<0.05)。进一步对糖尿病及肿瘤关系进行Logistic回归分析,糖尿病是恶性肿瘤发生的危险因素。结论 40岁以上人群,腰臀比、年龄、性别、退休、家族史、油炸食品、打鼾是糖尿病发生的危险因素,工作、咖啡、水果、鲜榨果蔬汁、跳舞是保护因素。糖尿病与肿瘤的发生风险之间存在明显相关性。Objective To study the relationship between the epidemiological characteristics of diabetes and cancer risk in residents over 40 years old. Methods From January 2021 to September 2021, 9880 participants over 40 years who were admitted to a tertiary Class A hospitals in Xi’an were selected. Among them, 1388 participants had diabetes. Questionnaire surveys, physical examination and blood test were used to analyze the relationship between the epidemiological characteristics of diabetes and cancer risk. Results Waist-to-hip ratio, gender and age are associated with blood glucose in the diabetes group. These are risk factors. Work is negatively associated with diabetes prevalence and is a protective factor, while retirement and family history are positively associated with diabetes prevalence and are risk factors. Coffee, soy products, fruits, freshly squeezed fruit and vegetable juice, and dancing are protective factors that can reduce the risk of diabetes. Fried food and snoring increase the risk of diabetes and are risk factors. Among the 9880 participants, 159 patients had cancer including 40 with breast cancer, 22 with endometrial cancer and 11 with colorectal cancer. The incidence of cancer was 4.0%(56 patients) in patients with diabetes, which was significantly higher than 1.2%(103 patients) of patients without diabetes(P<0.05). Further logistic regression analysis of the relationship between diabetes and cancer found that diabetes is a risk factor for the occurrence of malignant tumors. Conclusion For people over 40 years old, waist-to-hip ratio, age, gender, retirement, family history, fried food and snoring are risk factors for diabetes. Work, coffee, fruit, freshly squeezed fruit and vegetable juice, and dancing are protective factors. Diabetes was significantly associated with risk for cancer.

关 键 词：糖尿病 流行病学 肿瘤发生风险 相关性 

分 类 号：R73-31[医药卫生—肿瘤]