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作 者:中华医学会肠外肠内营养学分会 上海预防医学会微生态专业委员会 田宏亮[2] 赵笛 陈启仪 秦环龙[2] Society of Parenteral and Enteral Nutrition,Chinese Medical Association;Microecology Professional Committee of Shanghai Preventive Medicine Association;Chen Qiyi;Qin Huanlong
机构地区:[1]不详 [2]同济大学附属第十人民医院团队
出 处:《中华胃肠外科杂志》2022年第9期757-765,共9页Chinese Journal of Gastrointestinal Surgery
基 金:国家自然科学基金(81972221, 82100698);上海申康医院发展中心临床创新三年行动计划重大临床研究项目(SHDC2020CR1030B)。
摘 要:肠道菌群移植(FMT)目前已被临床医学指南及共识推荐用于多种肠道疾病治疗。供体的选择对FMT的安全性和有效性至关重要, 但在越来越多医疗机构尝试开展此项技术的临床实践中, 如何筛选与管理FMT供体成为急需规范的问题。鉴于此, 中华医学会肠外肠内营养学分会和上海预防医学会微生态专业委员会, 基于循证医学证据, 制定了供体筛选与管理专家共识, 包括网络筛选、临床筛选、捐献期间筛选与评估、供体管理标准建立、供体随访体系建立以及专业化服务保障等方面, 以期规范FMT供体的筛选与管理, 减少不良事件发生, 促进FMT的临床规范化应用。Fecal microbiota transplantation(FMT)has been recommended by clinical practical guidelines and consensus for the treatment of a variety of intestinal diseases,but in more and more medical institutions trying to develop this technology in clinical practice,how to screen and manage donors has become an urgent need for regulation.In view of this,based on evidence-based medical evidence,Society of Parenteral and Enteral Nutrition of Chinese Medical Association and Microecology Professional Committee of Shanghai Preventive Medicine Association jointly formulate an expert consensus on the screening and management of donors,including screening on the internet and in clinic,evaluation and selection during donation,establishment of the standard of donor management,the follow-up system and the professional support system,with a view to improving the quality of microbiota transplantation donors,reducing adverse events,and promoting the standardized clinical application of FMT.
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