外周型原始神经外胚层肿瘤/尤文肉瘤SPECT/CT显像的图像特征分析  

Imaging characteristics of peripheral primitive neuroectodermal tumor/Ewing sarcoma on SPECT/CT

作　　者：郭小楠[1] 牛锦云 李国权 GUO Xiao-nan;NIU Jin-yun;LI Guo-quan(Department of Nuclear Medicine,Xi'an Central Hospital,Xi'an 710006,China)

机构地区：[1]西安市中心医院核医学科,西安710006

出　　处：《中国肿瘤临床与康复》2022年第9期1050-1053,共4页Chinese Journal of Clinical Oncology and Rehabilitation

摘　　要：目的 探讨外周型原始神经外胚层肿瘤(PNET)/尤文肉瘤(ESFT)的SPECT/CT显像特点。方法 回顾性选取2008年1月至2021年5月间西安市中心医院诊治的37例PNET/ESFT患者,均采用CT扫描、全身SPECT骨扫描和SPECT/CT断层融合扫描,记录图像特征。结果 患者年龄5~67岁,男女比例3:1。患者临床症状以肿瘤伴有疼痛多见,持续时间数月,较长者可持续1年。发病部位骨盆15例,四肢10例,肩关节组成骨7例,脊柱5例。SPECT/CT显像为肿瘤体积较大,巨大软组织肿瘤伴骨质改变为主,软组织肿瘤呈病灶不摄取或仅轻度核素摄取,骨质改变以硬化性骨质破坏为主。结论 PNET/ESFT恶性程度较高,临床与病理表现多样,SPECT/CT显像可准确诊断病变数量及全身分布情况,利于患者早期诊断。Objective To analyze the imaging characteristics of primitive neuroectodermal tumor(PNET)/Ewing sarcoma family of tumors(ESFT) on single-photon emission computed tomography/computed tomography(SPECT/CT). Methods From January 2008 to May 2021, 37 patients with PNET/ESFT diagnosed and treated at Xi’an Central Hospital were retrospective selected. All patients underwent CT scans and whole body SPECT bone Scan and SPECT/CT tomographic fusion scan. Imaging characteristics were recorded. Results The included patients were 5 to 67 years old. The male to female ratio is 3:1. Most patients had tumors with pain as clinical symptoms which last for several months and even for 1 year. For the location of the disease, 15 patients had disease in the pelvic region, 10 in limbs, 7 in shoulder joints and 5 in spine. The characteristics of imaging on SPECT/CT showed that the tumor volume was relatively large, and the huge soft tissue tumors were mainly accompanied by bone changes. The soft tissue tumors show no uptake or only light nuclide uptake in the lesion, and the bone quality changes are mainly caused by sclerosing bone destruction Conclusion Peripheral primitive neuroectodermal tumor/Ewing sarcoma have high degree of malignancy, and its clinical and pathological manifestations are diverse. SPECT/CT imaging can accurately diagnose the number of lesions and the whole body distribution, which is conducive to the early diagnosis.

关 键 词：SPECT/CT PNET ESFT 诊断 标准摄取值 

分 类 号：R739.43[医药卫生—肿瘤]