SPECT/CT断层融合骨显像与常规骨扫描在肿瘤骨转移中的应用比较  

Comparison of the Application of SPECT/CT Tomographic Fusion Bone Imaging and Conventional Bone Scanning in Tumor Bone Metastasis

作　　者：廖俊伟 毕伟[1] 霍晓洋 侯珍文[1] Liao Junwei;Bi Wei;Huo Xiaoyang;Hou Zhenwen(Department of Nuclear Medicine,Dongguan People's Hospital,Dongguan,Guangdong 523000)

机构地区：[1]东莞市人民医院核医学科,广东东莞523000

出　　处：《现代医用影像学》2022年第9期1611-1614,1623,共5页Modern Medical Imageology

基　　金：东莞市社会科技发展(一般)项目,项目名称:化疗中期18F-FDG-PET/CT肿瘤代谢参数在淋巴瘤疗效评价及预后评估中的价值,项目编号:202050715001783。

摘　　要：目的:比较了单光子发射计算机断层成像术(Single-Photon Emission Computed Tomography/Computed Tomography,SPECT/CT)融合骨显像与常规骨扫描在肿瘤骨转移中的诊断效果。方法:选取2015年1月到2020年12月来我院接受检查的180例具备恶性肿瘤的患者,作为本次的研究对象。所有纳入对象均接受常规全身骨扫描与SPECT/CT局部融合骨显像检查,对比不同检查方式对肿瘤骨转移的诊断结果。结果:180例恶性肿瘤患者最终诊断为有肿瘤骨转移82例,无骨转移者98例。SPECT/CT显像诊断骨转移的特异性、准确性、阳性预测值均明显高于常规骨扫描检查(P<0.05),在敏感度和阴性预测值方面两种检查方式得到的结果并无明显差异(P>0.05)。结论:SPECT断层骨显像配合CT检查,结合了CT的精细的解剖结构和SPECT骨组织代谢的三维骨图像,病灶检出率对比常规骨扫描具有一定的优势,能够在肿瘤骨转移早期明确病情进展情况,指导医师及时为患者采取积极的治疗方案,有助于提升预后效果。因此患者行全身扫描检查时,结合局部SPECT/CT断层融合骨显像非常有必要。Objective:To compare the diagnostic effect of single-photon emission computed tomography(SPECT/CT)fusion bone imaging and conventional bone scanning in tumor bone metastasis.Methods:180 patients with malignant tumors who came to our hospital for examination(time interval:August 2019 and December 2020)were selected as the subjects of this study.All the included subjects underwent routine whole-body bone scan and SPECT/CT local fusion bone imaging examination to compare the diagnosis results of tumor bone metastasis by different examination methods.Results:180 patients with malignant tumors were finally diagnosed as having tumor bone metastasis in 82 cases and 98 cases without bone metastasis.The specificity,accuracy,and positive predictive value of SPECT/CT imaging in the diagnosis of bone metastases were significantly higher than those of conventional bone scans(P<0.05).The results obtained by the two inspection methods in terms of sensitivity and negative predictive value were not obvious Difference(P>0.05).Conclusion:SPECT tomographic bone imaging combined with CT examination,combined with the fine anatomical structure of CT and the three-dimensional bone image of SPECT bone tissue metabolism,the detection rate of lesions has certain advantages compared with conventional bone scanning,and it can clarify the disease in the early stage of bone metastasis Progress,instructing physicians to promptly adopt active treatment plans for patients,which will help improve the prognosis.Therefore,it is necessary to combine local SPECT/CT tomographic fusion bone imaging when the patient undergoes a whole body scan.

关 键 词：肿瘤骨转移 单光子发射计算机断层成像术 诊断价值 

分 类 号：R73-37[医药卫生—肿瘤]