Review of ex-vivo characterisation of corneal biomechanics  

作　　者：JunJie Wang XiaoYu Liu FangJun Bao Bernardo T.Lopes LiZhen Wang Ashkan Eliasy Ahmed Abass Ahmed Elsheikh 

机构地区：[1]Eye Hospital,Wenzhou Medical University,Wenzhou,China [2]The Institution of Ocular Biomechanics,Wenzhou Medical University,Wenzhou,China [3]Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education,School of Biological Science and Medical Engineering,Beihang University,Beijing,China [4]Beijing Advanced Innovation Centre for Biomedical Engineering,Beihang University,Beijing,China [5]School of Engineering,University of Liverpool,Liverpool,UK [6]Department of Ophthalmology,Federal Univerisity of Sao Paulo(UNIFESP),Sao Paulo,Brazil [7]National Institute for Health Research(NIHR)Biomedical Research Centre for Ophthalmology,Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology,London,UK

出　　处：《Medicine in Novel Technology and Devices》2021年第3期40-46,共7页医学中新技术与新装备（英文）

基　　金：This study was supported by the Zhejiang Provincial Natural Science Foundation of China under Grant(LY20H120001,LQ20A020008);the National Natural Science Foundation of China(82001924).

摘　　要：The evaluation of the corneal biomechanical behaviour has important clinical applications.To name a few,the accuracy of the intraocular pressure measurement,the study of corneal ectatic diseases and the assessment and optimisation of corneal surgical procedures are all highly influenced by corneal biomechanics.Over the last 45 years different ex-vivo methods were developed to study corneal biomechanical behaviour.Different tissue maintenance,support,loading systems,as well as different monitoring strategies of corneal deformations were employed.In this review,the most important and commonly used methods are outlined,including strip extensiometry,inflation,compression,indentation and tissue separation testing.Their particularities,applications,pros and cons and main applications are discussed.

关 键 词：EX-VIVO Corneal Biomechanics Experimental testing 

分 类 号：R73[医药卫生—肿瘤]