A Review: The Phytochemistry, Pharmacology, and Pharmacokinetics of Curcumae Longae Rhizoma(Turmeric)  

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作  者:Song-Tao Liu Sen-Wang Zheng A-Jiao Hou Jia-Xu Zhang Song Wang Xue-Jiao Wang Huan Yu Liu Yang 

机构地区:[1]Key Laboratory of Basic and Application Research of Beiyao(Heilongjiang University of Chinese Medicine),Ministry of Education,Harbin 150040,China

出  处:《World Journal of Traditional Chinese Medicine》2022年第4期463-490,共28页世界中医药杂志(英文)

基  金:supported by the Graduate Innovative Research Project Foundation of Heilongjiang University of Chinese Medicine(No.2022yjscx059);the Natural Science Foundation of Heilongjiang Province[No.LH2021H097];the National Natural Science Foundation Matching Project(No.2018PT02);the National Natural Science Foundation of China(No.81703684,81803690,and 81973604);The Special Funds from the Central Finance to Support the Development of Local Universities;the scientific research project of Heilongjiang Provincial Health Commission(No.20211313050171)。

摘  要:Curcumae Longae Rhizoma(CLR)is the rhizome of Curcuma longa L.Pharmacological studies show that CLR can be used to treat cervical cancer,lung cancer,lupus nephritis,and other conditions.In this paper,we review botany,traditional application,phytochemistry,pharmacological activity,and pharmacokinetics of CLR.The literature from 1981 to date was entirely collected from online databases,such as Web of Science,Google Scholar,China Academic Journals full-text database(CNKI),Wiley,Springer,PubMed,and ScienceDirect.The data were also obtained from ancient books,theses and dissertations,and Flora Reipublicae Popularis Sinicae.There are a total of 275 compounds that have been isolated from CLR,including phenolic compounds,volatile oils,and others.The therapeutic effect of turmeric has been expanded from breaking blood and activating qi in the traditional sense to antitumor,anti-inflammatory,antioxidation,neuroprotection,antibacterial,hypolipidemic effects,and other benefits.However,the active ingredients and mechanisms of action related to relieving disease remain ill defined,which requires more in-depth research and verification at a clinical level.

关 键 词:BOTANY Curcumae Longae Rhizoma PHARMACOKINETICS PHARMACOLOGY PHYTOCHEMISTRY traditional uses 

分 类 号:R284[医药卫生—中药学] R285[医药卫生—中医学]

 

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