光学相干断层扫描血管成像在帕金森病中应用的研究进展  

Research progress of optical coherence tomography angiography in Parkinson’s disease

作　　者：杨兰青 徐敏[1] 叶民[1] YANG Lan-qing;XU Min;YE Min(Department of Neurology,the Affiliated BenQ Hospital of Nanjing Medical University,Nanjing 210019,China)

机构地区：[1]南京医科大学附属明基医院神经内科,210019

出　　处：《临床神经病学杂志》2022年第4期311-314,共4页Journal of Clinical Neurology

摘　　要：帕金森病(PD)是一种中老年常见的神经退行性疾病。本病患者在黑质多巴胺能神经元进行性丢失和路易小体形成的同时,视网膜微血管也受到影响并发生改变。光学相干断层扫描血管成像(OCTA)是一种非侵入性生物成像技术,可以提供视网膜微血管的高分辨率图像。本文对近年来OCTA技术在PD方面的研究进展进行综述,以期对临床提供帮助。Parkinson’s disease(PD) is a common neurodegenerative disease in middle-aged and elderly people.Retinal microvascular is also impacted and changed when the progressive loss of dopaminergic neurons in the substantia nigra and the formation of Lewy bodies.Optical coherence tomography angiography(OCTA) is a noninvasive bioimaging technique that can provide high-resolution images of retinal microvascular.This paper review the recent progress of OCTA technology in PD for help in the clinic.

关 键 词：帕金森病 光学相干断层扫描血管成像 视网膜微血管 

分 类 号：R742.5[医药卫生—神经病学与精神病学]