神经影像技术在药物成瘾机制及治疗中的应用与挑战  

Application and challenges of neuroimaging technology in mechanisms and treatment of drug addiction

作　　者：袁凯 张杉 刘军[2] 喻大华[3] Kai Yuan;Shan Zhang;Jun Liu;Dahua Yu(School of Life Science and Technology,Xidian University,Xi′an 710126,China;Department of Radiology,the Second Xiangya Hospital of Central South University,Changsha 410011,China;Information Processing Laboratory,School of Information Engineering,Inner Mongolia University of Science and Technology,Baotou 014010,China)

机构地区：[1]西安电子科技大学生命科学技术学院,西安710126 [2]中南大学湘雅二医院放射科,长沙410011 [3]内蒙古科技大学信息工程学院,包头014010

出　　处：《中华医学杂志》2022年第35期2734-2737,共4页National Medical Journal of China

基　　金：国家自然科学基金(81871426,81871430,61971451);科技创新2030-“脑科学与类脑研究”(2022ZD0214500)。

摘　　要：神经影像技术可以无创地表征成瘾大脑结构和功能信息,揭示成瘾行为的神经机制,为脑刺激潜在靶点提供先验。神经影像技术在药物成瘾疾病中的研究、复吸预测、无创脑刺激疗效评估中都起到了重要作用,但也面临着诸多挑战。在此,我们对神经影像技术的分类与分析方法、在成瘾中的应用以及面临的挑战进行论述和探讨,以期推进神经影像技术在药物成瘾戒治工作中的应用。Neuroimaging technologies can non-invasively characterize the structure and function of addiction brain,reveal the neural mechanism of addictive behavior,and provide a priori for the potential targets of brain stimulation.Neuroimaging technologies has played an important role in the study of drug addiction diseases,relapse prediction,and therapeutic evaluation of non-invasive brain stimulations,but it also faces many challenges.In this manuscript,we discuss the classification and analysis methods of neuroimaging technologies,its application in addiction and challenges,thus to promote the application of neuroimaging technology in the treatment of drug addiction.

关 键 词：放射学 成瘾 神经影像 脑调控 

分 类 号：R749.61[医药卫生—神经病学与精神病学]