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作 者:龚贝贝[1] 韦彩云[1] 吴锋耀[1] 玉明柳 刘升[1] 陆宁[1] GONG Beibei;WEI Caiyun;WU Fengyao;YU Mingliu;LIU Sheng;LU Ning(The Fourth People's Hospital of Nanning,Guangxi AIDS Clinical Treatment Center(Nanning),Guangxi 530023 China)
机构地区:[1]南宁市第四人民医院广西艾滋病临床治疗中心(南宁),广西530023
出 处:《护理研究》2022年第20期3592-3597,共6页Chinese Nursing Research
基 金:南宁市科学研究与技术开发计划项目,编号:20193008⁃4。
摘 要:目的:探讨艾滋病(AIDS)机械通气病人早期肠内营养管理方案的临床应用效果。方法:构建艾滋病机械通气病人早期肠内营养管理方案,选取南宁市某三级甲等传染病专科医院重症监护病房(ICU)2019年1月-2020年12月收治的行机械通气治疗的艾滋病病人80例,按随机数字表法分为两组。观察组采用早期肠内营养管理方案,对照组采用传统肠内营养治疗、护理方案。比较两组干预后第7天和第14天营养及免疫指标、肠内营养7 d喂养达标率和喂养中断率、70%目标喂养量达标时间、干预后肠内营养不耐受症状发生率、机械通气时间、ICU住院时间等指标。结果:干预7 d后观察组肠内营养7 d喂养热量达标率(94.74%)较对照组(27.03%)升高,喂养中断率、70%目标喂养量达标时间、肠内营养不耐受发生率较对照组降低,两组比较差异均有统计学意义(P<0.01);干预第14天观察组血清清蛋白值、CD4^(+)T淋巴细胞计数较对照组升高,两组比较差异有统计学意义(P<0.01)。结论:艾滋病机械通气病人实施早期肠内营养管理方案,可提高病人喂养耐受性,降低喂养中断发生率,有效提高艾滋病机械通气病人营养免疫指标。Objective:To investigate the clinical application effect of the early enteral nutrition(EEN)management program in patients with acquired immunodeficiency syndrome(AIDS)who received mechanical ventilation(MV).Methods:To construct an EEN management program for AIDS patients with MV.A total of 80 cases of AIDS patients treated with MV who were admitted to the intensive care unit(ICU)of a tertiary grade A infectious disease hospital in Nanning from January 2019 to December 2020 were selected and divided into two groups according to the random number table method.The observation group received the EEN management program,and the control group received the traditional enteral nutrition treatment and nursing program.The nutritional and immune indexes,7⁃day enteral nutrition feeding compliance rate and feeding interruption rate,time to 70%of the target feeding amount,the incidence of enteral nutrition intolerance symptoms after the intervention,MV period,length of stay in ICU,and other indicators were compared between the two groups at 7 and 14 days after the intervention.Results:After 7 days of intervention,in the observation group,the 7⁃day feeding calorie compliance rate of enteral nutrition(94.74%)was higher than that in the control group(27.03%);the feeding interruption rate,time to 70%of the target feeding amount,and the incidence of enteral nutrition intolerance symptoms were lower than those of the control group;the difference was statistically significant(P<0.01).After 14 days of intervention,the serum albumin value and CD4^(+)T lymphocyte count in the observation group were higher than those in the control group,and the difference was statistically significant(P<0.01).Conclusions:Implementing an EEN management program in AIDS patients with MV could improve the patient's feeding tolerance,reduce the incidence of complications and feeding interruption,effectively improve the nutritional and immune indicators.
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