Urotensin Ⅱ level is elevated in inflammatory bowel disease patients  

作　　者：Yan Zhang Guo-Xun Chen 

机构地区：[1]Department of Gastroenterology,Affiliated Puren Hospital of Wuhan University of Science and Technology,Wuhan 430081,Hubei Province,China [2]Department of Nutrition,The University of Tennessee,Knoxville,TN 37996,United States

出　　处：《World Journal of Gastroenterology》2022年第35期5230-5232,共3页世界胃肠病学杂志（英文版）

摘　　要：It was reported that the urotensin Ⅱ(U-Ⅱ) level in inflammatory bowel disease(IBD) patients are significantly higher than in controls. To provide future guidance for the management of cardiovascular risk factors in IBD patients, the sample size of the current study appears to be limited, and more clinical samples to compare U-Ⅱ levels in IBD patients and controls are needed. This will clarify the possible roles of inflammation factors and related signaling pathways(like EPK1/2, NF-κB and Rho/ROCK) in the pathophysiology of IBD. Therefore, large multicenter studies should be done to confirm the findings and underlying mechanisms in the future.

关 键 词：Inflammatory bowel disease UrotensinⅡ Inflammatory factors High sensitivity C reactive peptide 

分 类 号：R574[医药卫生—消化系统]