Rare giant corneal keloid presenting 26 years after trauma:A case report  

作　　者：Shang Li Jiang Lei Ying-Hui Wang Xiao-Lin Xu Ke Yang Ying Jie 

机构地区：[1]Beijing Institute of Ophthalmology,Beijing Tongren Eye Center,Beijing Tongren Hospital,Capital Medical University,Beijing Ophthalmology and Visual Sciences Key Lab,Beijing 100005,China [2]Department of Ophthalmology,The First People's Hospital of Lanzhou City,Lanzhou 730050,Henan Province,China

出　　处：《World Journal of Clinical Cases》2022年第27期9776-9782,共7页世界临床病例杂志

摘　　要：BACKGROUND Corneal keloid is a rare clinical disease with an unknown etiology,which is easily misdiagnosed.Surgery is the most effective treatment but is rarely reported in the literature.Herein,we report the clinical features,histopathology,and surgical outcome of a giant corneal keloid with trophoblastic vessels and discuss the genesis of the mass.CASE SUMMARY A 36-year-old young man was admitted to the hospital because of a large mass on the surface of the left cornea.The patient had suffered an injury to his left eye at the age of 6-years-old;however,as the injury did not cause cornea perforation,he did not undergo treatment.Slit lamp exam showed a large,elevated,opaque lesion that covered the entire cornea and protruded from the surface of the eyeball.Anterior segment optical coherence tomography(AS-OCT) revealed a lesion of irregular density involving the anterior stroma.We suspected a secondary corneal fibroproliferative mass based on the clinical history,and slit lamp and AS-OCT findings.The patient subsequently underwent a superficial keratectomy and keratoplasty,and the final diagnosis of corneal keloid was confirmed by intraoperative histopathological examination.CONCLUSION Non-penetrating corneal trauma damages corneal epithelium basement membrane,initiating stromal fibrosis and causing corneal keloids.AS-OCT and biopsy confirm diagnosis.

关 键 词：Corneal keloid HISTOPATHOLOGY Immunohistochemical staining Anterior segment ocular coherence tomography Deep anterior lamellar keratoplasty Case report 

分 类 号：R779.6[医药卫生—眼科]