Rare leptin in non-alcoholic fatty liver cirrhosis:A case report  

作　　者：Yao-Bin Nong Hong-Na Huang Jing-Jing Huang Yuan-Qin Du Wen-Xuan Song De-Wen Mao Yue-Xue Zhong Rong-Huo Zhu Xi-Yu Xiao Rui-Xi Zhong 

机构地区：[1]The First Clinical Medical College,Guangxi University of Chinese Medicine,Nanning 530022,Guangxi Zhuang Autonomous Region,China [2]Department of Internal Medicine of Traditional Chinese Medicine,The First Affiliated Hospital of Guangxi University of Traditional Chinese Medicine,Nanning 530022,Guangxi Zhuang Autonomous Region,China [3]Department of Spleen and Stomach Liver Diseases,The First Affiliated Hospital of Guangxi University of Chinese Medicine,Nanning 530022,Guangxi Zhuang Autonomous Region,China [4]Department of Hepatology,The First Affiliated Hospital of Guangxi University of Traditional Chinese Medicine,Nanning,Guangxi Zhuang Autonomous Region,China

出　　处：《World Journal of Clinical Cases》2022年第28期10293-10300,共8页世界临床病例杂志

基　　金：Supported by Guangxi Provincial Natural Science Foundation of China,No.2022GXNSFBA035485 and No.2022GXNSFAA035460;Basic Ability Improvement Project of Young and Middle-aged Teachers in Guangxi Colleges and Universities,No.2019KY0313;the National Natural Science Foundation of China,No.81760845 and No.81403382;Innovation Project of Guangxi Graduate Education,No.YCSW2021220 and No.YCXJ2021056。

摘　　要：BACKGROUND Non-alcoholic fatty liver disease(NAFLD)-related cirrhosis is mainly caused by NAFLD by causing inflammation which leads to fibrosis.The role of leptin in NAFLD-related cirrhosis has been rarely reported.CASE SUMMARY This study presents the case of a 65-year-old male patient who was referred to The First Affiliated Hospital of Guangxi University of Chinese Medicine,Guangxi,Chi-na,for diagnosis and treatment for liver cirrhosis.Initially,the cause of liver cirrhosis was unknown.After radiology,laboratory examination,pathological results and analysis of the patient’s signs and symptoms,the case was finally diagnosed with final NAFLD-related cirrhosis.Although this study reports a single case,the findings might expand the understanding of leptin’s role in NAFLD-related cirrhosis and might provide a basis for the clinical diagnostic criteria,pathological features and treatment of NAFLD-related cirrhosis.CONCLUSION Although the occurrence of marasmus NAFLD-related cirrhosis is rare,it needs to be distinguished from other liver diseases,including viral hepatitis,drug-induced liver disease,Wilson’s disease and autoimmune liver disease.Aggressive treatment is needed to prevent the progression of NAFLD-related cirrhosis.

关 键 词：Non-alcoholic fatty cirrhosis Leptin type Nonalcoholic fatty liver disease Case report 

分 类 号：R575.2[医药卫生—消化系统]