一种乙基香兰素共晶的合成、结构与表征  

Synthesis, Structure and Characterization of a Co-crystal of Ethyl Vanillin

作　　者：夏童 李鑫[1] 王子宁 凡长坡 孙伯旺 Xia Tong;Li Xin;Wang Zining;Fan Changpo;Sun Bowang(School of Chemistry and Chemical Engineering,Southeast University,Nanjing 211189;School of Pharmaceutical and Chemical Engineering,Chengxian College,Southeast University,Nanjing 210088,China)

机构地区：[1]东南大学化学化工学院,江苏南京211189 [2]东南大学成贤学院制药与化学化工学院,江苏南京210088

出　　处：《广东化工》2022年第19期40-42,共3页Guangdong Chemical Industry

摘　　要：乙基香兰素由于其强烈的独特香子兰气味,作为香味添加剂被广泛应用于食品药品、化妆品等领域,但其非常不稳定,香气香味易挥发。为了提高乙基香兰素的热稳定性,实现香气的缓慢释放,共结晶被认为是香料化学领域实现这一目标的有效途径。本文以乙基香兰素为原料,尿素为配体,通过溶剂挥发法合成乙基香兰素-尿素共晶化合物。用粉末X射线衍射(PXRD)、单晶X射线衍射(SXRD),热重分析(TGA)和红外光谱(FT-IR)对其进行结构和性质的表征,为香兰素类共晶潜香化合物的合成和应用提供理论支撑,一方面提高乙基香兰素的贮藏稳定性,另一方面提高其热稳定性。Ethyl vanillin is widely used as a flavor additive in food, medicine, cosmetics and other fields due to its strong and unique vanilla odor, but it is very unstable and its aroma and fragrance are volatile. In order to improve the thermal stability of ethyl vanillin and realize the slow release of aroma, co-crystallization is considered as an effective way to achieve this goal in the field of fragrance chemistry. In this paper, ethyl vanillin-urea co-crystal compound was synthesized by solvent evaporation method using ethyl vanillin as raw material and urea as ligand. Its structure and properties were characterized by powder X-ray diffraction(PXRD), single crystal X-ray diffraction(SXRD), thermogravimetric analysis(TGA) and infrared spectroscopy(FT-IR). The synthesis and application of the compound provide theoretical support, on the one hand to improve the storage stability of ethyl vanillin, on the other hand to improve its thermal stability.

关 键 词：乙基香兰素 潜香物质 共晶 烟用香料 合成 

分 类 号：TQ[化学工程]