补肾活血促排汤联合针刺治疗肾虚血瘀型未破裂卵泡黄素化综合征  

Curative efficacy of Bushen Huoxue Ovulation Stimulating Decoction combined with acupuncture in the treatment of Luteinized Unruptured Follicle Syndrome of kidney deficiency and blood stasis type

作　　者：欧阳文 冯雪琼 刘玉兰 刘凤萍 OU Yang-wen(Department of Gynecology,The Traditional Chinese Medicine Hospital of Qingyuan City,Qingyuan 511500,China)

机构地区：[1]清远市中医院妇科,广东清远511500 [2]清远市中医院功能科,广东清远511500

出　　处：《牡丹江医学院学报》2022年第5期51-55,共5页Journal of Mudanjiang Medical University

基　　金：广东省中医药局科研项目(20211460)。

摘　　要：目的探讨补肾活血促排汤联合针刺治疗肾虚血瘀型未破裂卵泡黄素化综合征(LUFS)的疗效。方法将清远市中医院妇科门诊2020年1月至2021年7月接收的肾虚血瘀型LUFS患者62例作为研究对象,按照治疗方式不同分为对照组(n=34例)与研究组(n=28例);对照组给予肌注人绒毛膜促性腺激素(HCG)治疗;研究组给予补肾活血促排汤联合针刺治疗,连续治疗3个月经周期,期间妊娠则终止后续周期治疗;比较两组患者的妊娠率、排卵率,比较治疗前后的卵巢动脉血流参数[动脉血流搏动指数(PI)、阻力指数(RI)、收缩期与舒张期血流速度比值(S/D)、血管化指数(VI)、血流指数(FI)及血管化血流指数(VFI)]及血清性激素水平[促卵泡生成激素(FSH)、促黄体生成激素(LH)、雌二醇(E2)、孕酮(P)、睾酮(T)、催乳激素(PRL)]。结果研究组总妊娠率显著高于对照组(P<0.05);研究组排卵率显著高于对照组(P<0.05);研究组治疗后的PI、RI低于对照组治疗后,治疗后的VI、FI及VFI高于对照组治疗后(P<0.05);研究组治疗后的FSH、E2、LH及P水平高于对照组同期(P<0.05)。结论补肾活血促排汤联合针刺治疗LUFS疗效优于肌注HCG,可降低卵巢动脉血流阻力,改善卵巢血流灌注,提升血清性激素水平,促进排卵,提升妊娠率。Objective To explore the curative efficacy of Bushen Huoxue Ovulation Stimulating Decoction combined with acupuncture in the treatment of Luteinized Unruptured Follicle Syndrome(LUFS)of kidney deficiency and blood stasis type.Methods A total of 62 patients with kidney deficiency and blood stasis type LUFS received from the Gynecological Clinic of Qingyuan Traditional Chinese Medicine Hospital from January 2020 to July 2021 were selected as the research objects.According to different treatment methods,they were divided into the control group(n=34 cases)and the study group(n=28 cases).The control group were given intramuscular injection of human chorionic gonadotropin(HCG).The study group were given Bushen Huoxue Ovulation Stimulating Decoction combined with acupuncture treatment for 3 consecutive menstrual cycles,when decting pregnancy,the subsequent cycles of treatment were terminated.The pregnancy rate and ovulation rate of the two groups were compared.The ovarian arterial blood flow parameters before and after treatment were also compared[arterial blood flow pulsation index(PI),resistance index(RI),systolic and diastolic blood flow velocity ratio(S/D),Vascularization Index(VI),Blood Flow Index(FI)and Vascularized Blood Flow Index(VFI)]and serum sex hormone levels[Follicle Stimulating Hormone(FSH),Luteinizing Hormone(LH),Estradiol(E2),Progesterone(P),testosterone(T),prolactin(PRL)].Results The total pregnancy rate of the study group were significantly higher than that of the control group(P<0.05).The ovulation rate of the study group was significantly higher than that of the control group(P<0.05).The PI and RI of the study group after treatment were lower than that of the control group after treatment.The VI,FI,and VFI of the study group were higher than that of the control group after treatment,and the difference were statistically significant(P<0.05).The levels of FSH,E2,LH,and P in the study group after treatment were higher than that of the control group during the same period,and the difference were statist

关 键 词：补肾活血促排汤 针刺 肾虚血瘀型 未破裂卵泡黄素化综合征 卵巢动脉血流 血清性激素 排卵 妊娠 

分 类 号：R743.3[医药卫生—神经病学与精神病学]