Transcription Factor MAFA Regulates Mechanical Sensation by Modulating Piezo2 Expression  

作　　者：Chang-ming Wang Dustin P.Green Xinzhong Dong 

机构地区：[1]The Solomon H.Snyder Department of Neuroscience,Johns Hopkins University School of Medicine,Baltimore,MD,21205,USA [2]Department of Neuroscience,Cell Biology,and Anatomy,University of Texas Medical Branch,Galveston,TX,USA [3]Solomon H.Snyder Department of Neuroscience,Johns Hopkins University School of Medicine,Baltimore,MD,21205,USA [4]Department of Dermatology,Johns Hopkins University School of Medicine,Baltimore,MD,21205,USA [5]Department of Neurosurgery,Johns Hopkins University School of Medicine,Baltimore,MD,21205,USA [6]Howard Hughes Medical Institute,Chevy Chase,MD,USA

出　　处：《Neuroscience Bulletin》2022年第8期933-937,共5页神经科学通报（英文版）

基　　金：This work was supported by the Howard Hughes Medical Institute.We thank Dennis Chang and Michael J.Caterina for assisting with the data analysis.

摘　　要：Dear Editor,Essential for survival,mechanical sensation is detected and transmited to the spinal cord by primary sensory afferents and their cell bodies located in the dorsal root ganglia(DRG).Multiple types of mechanically sensitive DRG neurons have been identified that mediate various mechanosensation modalities(e.g.non-painful versus painful).

关 键 词：SENSATION MODALITIES ESSENTIAL 

分 类 号：R338[医药卫生—人体生理学]