纤维素基生物材料在细胞培育肉生产中的应用  

A Review of the Application of Cellulose-Based Biomaterials for Cultured Meat Production

作　　者：唐雨楠 史陈晨 杨明[1] 盛奎川[1] 张玺铭 TANG Yunan;SHI Chenchen;YANG Ming;SHENG Kuichuan;ZHANG Ximing(College of Biosystems Engineering and Food Science,Zhejiang University,Hangzhou 310058,China)

机构地区：[1]浙江大学生物系统工程与食品科学学院,浙江杭州310058

出　　处：《食品科学》2022年第19期295-307,共13页Food Science

基　　金：上海食未生物科技有限公司(CellX)资助项目。

摘　　要：随着细胞培育肉研究的兴起,应用于细胞培育肉生产的可食用支架受到高度关注。纤维素具有丰富易得、可食用、非动物源、成本低、可商业化生产等特点,这些都展示了纤维素用于细胞培育肉的重要潜力。本综述首先介绍了不同种类纤维素(植物纤维素、细菌纤维素)的基本理化性质,其次围绕支架的一系列特定结构(多孔、定向、球形结构、天然精密结构、可定制结构),提出了针对纤维素基细胞培育肉支架的制备方法,最后讨论了纤维素应用于细胞培育肉支架中的主要挑战,并提供了可能的解决方案,以期为低成本、连续化生产纤维素基支架以及良好培育肌肉、脂肪细胞提供参考。As cultured meat research has become popular, edible scaffolds that can be used in cultured meat production have attracted great attention. Cellulose is characterized by abundant supply, easy availability, edibility, non-animal source, low cost and commercial scale production, showing potential application in cultured meat. In this review, we introduce the basic physical and chemical properties of different kinds of cellulose(plant-based cellulose and bacterial cellulose). Next, based on a series of specific structures of scaffolds(porous, directional, spherical, natural precise and customizable structure), we propose methods for preparing cultured meat scaffolds based on cellulose. Finally, we discuss the key challenges for the application of cellulose in cultured meat scaffolds and propose possible solutions. We hope that this review will be helpful for the cost-effective and continuous production of cellulose-based scaffolds and good cultivation of muscle and fat cells.

关 键 词：纤维素衍生物 去细胞植物组织 支架 微载体 水凝胶 生物墨水 细胞培育肉 

分 类 号：TS251.1[轻工技术与工程—农产品加工及贮藏工程] R318.08[轻工技术与工程—食品科学与工程]