经角膜缘切口手术治疗伴复杂眼前节异常的婴幼儿永存胎儿血管症的效果  

Surgery through corneal incisions for infant persistent fetal vasculature with complicated anterior segment anamolies

作　　者：刘敬花 李松峰 邓光达 杨文利 陈伟 李亮 麻婧 原铭贞 卢海 Liu Jinghua;Li Songfeng;Deng Guangda;Yang Wenli;Chen Wei;Li Liang;Ma Jing;Yuan Mingzhen;Lu Hai(Beijing Tongren Eye Center,Beijing Tongren Hospital,Capital Medical University,Beijing Key Laboratory of Ophthalmology and Visual Sciences,Beijing 100730,China)

机构地区：[1]首都医科大学附属北京同仁医院,北京同仁眼科中心,眼科学与视觉科学北京市重点实验室,100730

出　　处：《眼科》2022年第5期360-363,共4页Ophthalmology in China

摘　　要：目的探讨经角膜缘切口晶状体玻璃体切除手术治疗伴复杂眼前节异常的婴幼儿永存胎儿血管症(PFV)的初期临床效果。设计回顾性病例系列。研究对象2019年5月至2022年1月,于北京同仁医院眼科诊断为伴复杂眼前节异常的PFV、并行经角膜缘切口晶状体玻璃体切除术的17例(17眼)患者。男性10例,平均月龄(13.4±9.2)个月。方法回顾性分析患者的病历资料,患者平均随访(24.5±10.6)个月。观察术后视力及手术并发症情况。主要指标视力、瞳孔区屈光间质混浊改善情况、并发症情况。结果末次随访时,术前无固视的12眼中9眼固视改善;术前17眼屈光间质全部混浊,术后17眼全部屈光间质清晰,随访期间瞳孔区增殖膜复发导致屈光间质再次混浊4眼,再次手术切除瞳孔区增殖膜后未再复发;未见术中及术后眼内出血、视网膜脱离、眼内炎等并发症。结论伴复杂眼前节异常的婴幼儿PFV经角膜缘切口晶状体切除联合玻璃体切除术后可获得视功能和眼局部解剖结构的改善。(眼科,2022,31:360-363)Objective To investigate short-term clinical effects of infant patients with persistent fetal vasculature(PFV)with complicated anterior segment anamolies,treated by lensectomy combined with vitrectomy through corneal incisions.Design Retrospective case series.Participants Patients diagnosed with PFV with complicated anterior segment anamolies,and underwent lensectomy combined with vitrectomy through corneal incisions in Beijing Tongren hospital from May 2019 to January 2022 were studied.Seventeen patients(17 eyes)including 10 males,with an average age of(13.4±9.2)months were included.Methods The clinical data of the patients were retrospectively described.Pre-and postoperative visual acuity and postoperative complications were observed.Main Outcome Measures Visual acuity,changes of opacity of the optical media of the pupillary zone and postoperative complications.Results At last visit,9 of the 12 patients had postoperative fix and follow ability of visual acuity improvement compared with that of preoperative,None patients had clear optical media of the pupillary zone preoperatively,and all the 17 patients had clear optic media postoperatively;4 eyes complicated with postoperative recurrent pupil membrane formation,which needed further operation;no cases with intraoperative or postoperative intraocular hemorrhage,secondary retinal detachment or ophthalmitis were observed.Conclusion Infants with PFV complicated anterior segment anamolies may have optimistic visual and anatomical prognosis after surgical treatment of lensectomy combined with vitrectomy through corneal incisions.(Ophthalmol CHN,2022,31:360-363)

关 键 词：永存胎儿血管症/外科学 婴幼儿 

分 类 号：R779.6[医药卫生—眼科]