临床电生理技术评估脓毒症相关性脑病的研究进展  

Research Progress in Clinical Electrophysiological Assessment of Patients with Sepsis-Associated Encephalopathy

作　　者：周梦露 金光勇 席绍松 陈嘉伊 梁栋诚 ZHOU Menglu;JIN Guangyong;XI Shaosong;CHEN Jiayi;LIANG Dongcheng(Department of Neurology,The Affiliated Hospital of Hangzhou Normal University,Hangzhou 310015,China;Department of Intensive Care Unit,Affiliated Hangzhou First People’s Hospital,Zhejiang University School of Medicine,Hangzhou 310006,China;Department of Intensive Care Unit,The Affiliated Hospital of Hangzhou Normal University,Hangzhou 310015,China)

机构地区：[1]杭州师范大学附属医院神经内科,杭州310015 [2]浙江大学医学院附属杭州市第一人民医院重症医学科,杭州310006 [3]杭州师范大学附属医院重症医学科,杭州310015

出　　处：《中国医学科学院学报》2022年第5期876-884,共9页Acta Academiae Medicinae Sinicae

基　　金：国家自然科学基金(82002008);浙江省卫生健康科技计划面上项目(2021KY894);杭州市卫生科技计划一般项目(A20220388);杭州市医学重点学科建设基金(OO20200485)。

摘　　要：脓毒症相关性脑病(SAE)是由中枢神经系统以外的感染引起的弥漫性脑功能障碍,临床常见且与不良预后显著相关。评估、诊断SAE的流程尚不成熟。临床上,镇静治疗、机械通气等许多因素可能导致SAE的评估困难,而使用电生理检查有助于评估或诊断SAE。本文对脑电图、体感诱发电位等电生理技术监测SAE的相关文献进行综述,以期为临床评估、诊断SAE提供依据。Sepsis-associated encephalopathy(SAE)caused by infections outside the central nervous system always presents extensive brain damage.It is common in clinical practice and associated with a poor prognosis.There are problems in the assessing and diagnosing of SAE.Many factors,such as sedation and mechanical ventilation,make it difficult to assess SAE,while electrophysiological examination may play a role in the assessment.We reviewed the studies of electrophysiological techniques such as electroencephalography and somatosensory evoked potentials for monitoring SAE,hoping to provide certain evidence for the clinical evaluation and diagnosis of SAE.

关 键 词：脓毒症相关性脑病 脑电图 体感诱发电位 

分 类 号：R741.044[医药卫生—神经病学与精神病学]