1990—2019年中国主要消化系统恶性肿瘤发病变化分析  

Incidence of Major Digestive System Cancers in China,1990—2019

作　　者：肖文博 朱广涵 朱云 王媛 XIAO Wen-bo;ZHU Guang-han;ZHU Yun;WANG Yuan(Department of Epidemiology and Biostatistics,School of Public Health,Tianjin Medical University,Tianjin 300070,China)

机构地区：[1]天津医科大学公共卫生学院流行病与卫生统计学系,天津300070

出　　处：《中国肿瘤》2022年第9期693-700,共8页China Cancer

基　　金：中国营养学会—振东国人体质与健康研究基金(CNS-ZD2020-82)。

摘　　要：[目的]描述1990—2019年中国主要消化系统恶性肿瘤发病及变化情况。[方法]采用全球疾病负担研究2019(GBD2019)数据,采用发病人数和发病率评价消化系统肿瘤发病水平,利用Joinpoint软件分析1990—2019年5种主要消化系统恶性肿瘤发病率的时间变化趋势,描述和评价消化系统恶性肿瘤发病及变化情况。[结果]2019年我国主要消化系统恶性肿瘤中粗发病率排名前5名分别为胃癌(43.09/10万)、结直肠癌(42.74/10万)、食管癌(19.55/10万)、肝癌(14.80/10万)和胰腺癌(8.08/10万)。除肝癌外,其余病种粗发病率相比1990年均有所上升,年龄标化后胃癌、食管癌和肝癌的标化发病率均下降,结直肠癌和胰腺癌的标化发病率仍然上升。[结论]中国消化系统恶性肿瘤疾病负担较重,30年间胃癌始终是我国发病首位的消化系统恶性肿瘤,结直肠癌疾病负担明显增加。49岁以上男性是消化系统恶性肿瘤的高危人群。[Purpose]To analyze the incidence of major digestive system cancers in China from1990 to 2019.[Methods]Data were collected from Global Burden of Disease study 2019(GBD2019).Number of new cases and incidence were used to assess the incidence and trends of major digestive system cancers.Joinpoint software was used to analyze the trends of incidence from 1990 to 2019.[Results]The incidence of top 5 digestive system cancers was stomach cancer(43.09/105),colorectal cancer(42.74/105),esophageal cancer(19.55/105),liver cancer(14.80/105)and pancreatic cancer(8.08/105)in 2019.Crude incidence was increased in 2019 except liver cancer compared with 1990.After age-standardized,the incidence of stomach cancer,esophageal cancer and liver cancer was decreased,while the incidence of colorectal cancer and pancreatic cancer was increased.[Conclusion]The burden of digestive system cancers is still heavy in China.Stomach cancer has been ranked the top of incidence in all digestive system cancers in the past 30 years.The burden of colorectal cancer has been increased dramatically.Men over 49 years old are at high risk of digestive system cancers.

关 键 词：消化系统肿瘤 发病 疾病负担 中国 

分 类 号：R73-31[医药卫生—肿瘤] R735[医药卫生—临床医学]