天然产物丹皮酚的衍生物开发利用研究  

On the Development and Utilization of Derivatives of Natural Product Paeonol

作　　者：王乙颖 张必荣 张志军 张宁琪 刘波[1] 刘洋[1] 田光辉[1] WANG Yi-ying;ZHANG Bi-rong;ZHANG Zhi-jun;ZHANG Ning-qi;LIU Bo;LIU Yang;TIAN Guang-hui(School of Chemistry and Environment Science,Shaanxi University of Technology,Hanzhong 723001,Shaanxi,China;Shaanxi Tiangu Pharmaceutical Co.,Ltd.,Chenggu 723212,Shaanxi,China)

机构地区：[1]陕西理工大学化学与环境科学学院,陕西汉中723000 [2]陕西天谷药业有限公司,陕西城固723212

出　　处：《江苏调味副食品》2022年第3期4-6,共3页Jiangsu Condiment and Subsidiary Food

基　　金：陕西省科技厅社会发展科技攻关项目(2021SF-382);陕西省教育厅专项科研计划项目(21JK0569);陕西省教育厅重点实验室项目(21JS003);陕西理工大学2022年研究生创新基金项目(SLGYCX2227)。

摘　　要：丹皮酚是从牡丹、芍药等植物中提取出来的一种天然有机物,分子结构中含有甲氧基、酚羟基、乙酰基等多个活性位点,形成了其结构修饰的依据。以丹皮酚为先导物可合成席夫碱型衍生物、NO供体型衍生物、阿魏酸丹皮酚酯、查尔酮等活性物质。综述丹皮酚及其衍生物的合成,为丹皮酚衍生物的开发利用提供理论依据。Paeonol is a kind of natural organic compounds extracted from plants such as peony and peony.Its molecular structure contains many active sites such as methoxy,phenolic hydroxyl and acetyl groups,which forms the basis for its structural modification.The active substances such as Schiff base derivatives,NO donor derivatives,paeonol ferulic ester and chalcone can be synthesized with paeonol as the lead.The synthesis of paeonol and its derivatives was reviewed to provide theoretical basis for the development and utilization of paeonol derivatives.

关 键 词：丹皮酚 衍生物 合成 

分 类 号：TS201[轻工技术与工程—食品科学]