Probable beneficial effects of black seeds (Nigella sativa) in the management of langya henipavirus infection  

作　　者：Naina Mohamed Pakkir Maideen 

机构地区：[1]PhD.Pharmacologist,Dubai Health Authority,Dubai,The United Arab Emirates.

出　　处：《Food and Health》2022年第4期1-3,共3页食品和健康（英文）

摘　　要：Background:The patients with Langya henipavirus(LayV)infection are managed mainly with symptomatic treatment and supportive care.Objective:This review article focuses on the beneficial effects of black seeds(Nigella sativa)in the management of Langya henipavirus(LayV)infection.Methods:The literature was searched in online databases,including Medline/Pubmed/PMC,Google Scholar,Science Direct,Ebsco,Scopus,Web of Science,Embase,and reference lists,to identify published studies,which established beneficial effects of black seeds(N.sativa)related to signs and symptoms of LayV infection.Results:Black seeds(N.sativa)have shown potential antiviral,bronchodilatory,antihistaminic,antitussive,hepatoprotective,renoprotective,anti-inflammatory,antioxidant,and immunomodulatory properties in various clinical,animal,in-vitro,in-vivo,and in-silico studies,which would help the patients with LayV infection.Conclusion:N.sativa would be a potential herbal candidate in the management of LayV infection along with symptomatic treatment and supportive care,to prevent further deterioration,and hospitalization.The safety and efficacy of N.sativa in patients with LayV infection would further be established by future randomized controlled clinical trials.

关 键 词：Langya henipavirus Hendra virus Nipa virus Nigella sativa black seeds kalonji THYMOQUINONE 

分 类 号：R73[医药卫生—肿瘤]