分化型甲状腺癌患者^(131)I治疗后唾液腺功能变化的诊疗进展  

Progress in diagnosis and treatment of salivary gland function changes in patients with differentiated thyroid cancer after ^(131)I treatment

作　　者：秦洋洋 付巍[1] Qin Yangyang;Fu Wei(Department of Nuclear Medicine,Affiliated Hospital of Guilin Medical College University,Guilin 541001,China)

机构地区：[1]桂林医学院附属医院核医学科,桂林541001

出　　处：《国际放射医学核医学杂志》2022年第7期419-424,共6页International Journal of Radiation Medicine and Nuclear Medicine

摘　　要：唾液腺功能受损是头颈部肿瘤患者放化疗中常见的不良反应,其对患者的生活质量及治疗效果产生严重影响,唾液腺功能受损发生率随着头颈部疾病发病率的增高而增高,亟需明确的防治手段。目前已有大量国内外研究结果揭示了唾液腺功能放射性损伤的部分机理并提供了一些防治措施予以临床参考。笔者重点综述由^(131)I治疗引起的唾液腺功能损伤的机制、症状、诊断及防治措施。The impairment of salivary gland function is a common adverse reaction in radiotherapy and chemotherapy of head and neck tumors,which has a serious impact on the quality of life and treatment effect of patients.The incidence of salivary gland dysfunction increases with the increase of the incidence of head and neck diseases.Clear prevention and treatment methods are urgently needed.At present,a large number of domestic and foreign studies have revealed the possible mechanism of the impaired salivary gland function caused by radiation therapy and provided some prevention and treatment measures for clinical reference.This review focuses on the mechanism,symptoms,diagnosis and prevention of salivary gland dysfunction caused by ^(131)I therapy.

关 键 词：碘放射性同位素 分化型甲状腺癌 钠碘转运体 唾液腺功能损伤 

分 类 号：R736.1[医药卫生—肿瘤]