^(131)I致分化型甲状腺癌患者唾液腺辐射损伤及其防治的研究进展  

Research progress on radiation injury of salivary gland and its prevention and treatment in patients with differentiated thyroid cancer induced by ^(131)I

作　　者：仝慧敏 杨素云[1] 程艳[1] Tong Huimin;Yang Suyun;Cheng Yan(Department of Nuclear Medicine,the First Hospital of Shanxi Medical University,Taiyuan 030001,China)

机构地区：[1]山西医科大学第一医院核医学科,太原030001

出　　处：《国际放射医学核医学杂志》2022年第7期425-429,共5页International Journal of Radiation Medicine and Nuclear Medicine

基　　金：山西省重点研发计划项目(201903D321194);山西省基础研究项目(20210302124411)。

摘　　要：^(131)I治疗分化型甲状腺癌(DTC)的技术成熟、效果显著,是DTC患者术后综合治疗的主要方法之一,目前已被广泛应用于临床。但其造成的唾液腺辐射损伤(口干、腮腺肿痛、味觉改变等)会对DTC患者的生活质量造成一定影响。近年来,各种唾液腺辐射损伤防护剂层出不穷,但其确切疗效较为局限,且治疗方案尚未规范统一。笔者就DTC患者术后行^(131)I治疗对唾液腺的辐射损伤及其防治的研究进展进行综述。^(131)I therapy for differentiated thyroid cancer(DTC)is a mature technology with remarkable effects.As one of the main methods of postoperative comprehensive treatment for patients with DTC,it has been widely used in clinical.But the resulting manifestations of salivary gland radiation injury(dry mouth,parotid gland swelling pain,and taste alteration,etc.)have a certain impact on DTC patients'survival quality.In recent years,various salivary gland radiation injury protective agents have emerged,but their exact efficacy is limited and the treatment plan has not been standardized and unified.The author reviews the research progress on radiation injury of salivary gland and its prevention and treatments in DTC patients treated with ^(131)I after operation.

关 键 词：涎腺炎 分化型甲状腺癌 碘放射性同位素 辐射损伤 

分 类 号：R736.1[医药卫生—肿瘤] R818[医药卫生—临床医学]