经颈静脉肝脏穿刺活检术临床应用112例  

Clinical application of transjugular liver puncture biopsy: preliminary results in 112 patients

作　　者：向童 王小泽 晏玉玲 王毅 罗薛峰[1] 杨丽[1] XIANG Tong;WANG Xiaoze;YAN Yuling;WANG Yi;LUO Xuefeng;YANG Li(Deparment of Gastroenterology Sichuan Uninersity-Uninersily of Ooford Huaxi Joint Center for Gastrointestinal Cancer West China Hospial of Sichuan Uniersity,Chengdu,Sichuan Province 610041,China)

机构地区：[1]四川大学华西医院消化内科,四川大学-牛津大学华西消化道肿瘤联合研究中心,成都610041

出　　处：《介入放射学杂志》2022年第9期901-904,共4页Journal of Interventional Radiology

基　　金：四川省科技厅国际合作项目(2020YFH0089);四川大学华西医院临床研究孵化项目(2019HXFH055)。

摘　　要：目的 评价经颈静脉肝脏穿刺活检术(TJLB)临床应用的效果和安全性。方法 收集2019年3月至2020年12月于四川大学华西医院接受TJLB的112例患者临床资料,分析患者基本信息、TJLB适应证、并发症以及肝脏组织标本质量。结果112例接受TJLB患者中男43例,女69例,年龄14~75岁。凝血功能障碍70例(62.5%),肝周积液或中量以上腹腔积液37例(33.0%),体质量指数≥30.0 kg/m24例(3.6%)。111例(99.1%)成功获取组织标本,其中109例(97.3%)患者肝脏组织标本可用于病理诊断,术后8例(7.1%)出现轻微并发症,无严重并发症发生。结论 TJLB是一种安全有效的介入技术,尤其适用于有经皮肝脏穿刺活检术禁忌患者。Objective To evaluate the clinical efficacy and safety of transjugular liver biopsy(TJLB).Methods The clinical data of 112 patients, who received TJLB at West China Hospital of Sichuan University between March 2019 and December 2020, were retrospectively analyzed. The patients’ basic information, TJLB indications, complications, and the quality of liver tissue specimens were analyzed.Results Of the 112 patients receiving TJLB, 43 were males and 69 were females, aged 14-75 years. Coagulation disorders was detected in 70 patients(62.5%), perihepatic effusion or moderate ascites was observed in37 patients(33.0%), and body mass index(BMI)≥30.0kg/m2was seen in 4 patients(3.6%). Successful sampling of liver tissues was accomplished in 111 patients(99.1%), and in 109 patients(97.3%) the obtained liver tissue specimens met the requirements for making a definite pathological diagnosis. After TJLB, 8 patients(7.1%)developed minor complications, and no serious complications occurred. Conclusion TJLB is a safe and effective interventional technique. This technique is especially suitable for patients who have contraindications to percutaneous liver biopsy.(J Intervent Radiol, 2022, 31: 901-904)

关 键 词：肝脏活检 经颈静脉 经皮穿刺 介入放射学 

分 类 号：R5755[医药卫生—消化系统]