Lacrimal sac lymphoma: a case series and literature review  

作　　者：Feng-Xi Meng Han Yue Yi-Qun Yuan Rui Zhang Yi-Fei Yuan Ying-Wen Bi Jiang Qian 

机构地区：[1]Department of Ophthalmology,Eye&ENT Hospital of Fudan Universityy,Shanghai 200031,China [2]Laboratory of Myopia,Chinese Academy of Medical Sciencesy,Shanghai 200031,China [3]NHC Key Laboratory of Myopia,Fudan Universityy,Shanghai 200031,China [4]Department of Pathology,Eye&ENT Hospital of Fudan University,Shanghai 200031,China

出　　处：《International Journal of Ophthalmology(English edition)》2022年第10期1586-1590,共5页国际眼科杂志（英文版）

基　　金：Supported by the National Natural Science Foundation of China(No.81970835);the Science and Technology Commission of Shanghai Municipality,China(No.20Y11911200);。

摘　　要：AIM: To study the clinical and pathological characteristics of the lacrimal sac lymphoma, which is rare but it is the major type of non-epithelial malignant tumor in the lacrimal sac region. METHODS: Sixty-four cases of malignant lacrimal sac tumors in our hospital from 1986 to 2020 were retrospectively reviewed. Eight cases of lacrimal sac lymphoma were carefully reviewed. RESULTS: There were five mucosal-associated lymphoid tissue(MALT) lymphomas, one diffused large B-cell lymphoma, one NK/T cell lymphoma, and one mantle cell lymphoma. All eight patients represented symptoms of epiphora with swelling in the lacrimal sac for a certain period of time and showed no signs of systemic involvement at the first time of clinical visits. They had received either chemotherapy or radiotherapy after surgery. Long-term follow-up(from 11 to 220 mo) showed that, except one patient with MALT lymphoma died for unknown reasons at 104 mo after surgery, the other 7 patients were all alive with no signs of local recurrence, neither in other organs. CONCLUSION: Non-epithelial malignant tumors of the lacrimal sac are rare and lymphoma is the major subtype.

关 键 词：lacrimal sac tumor lacrimal drainage apparatus non-epithelial lacrimal sac tumor LYMPHOMA mucosal-associated lymphoid tissue lymphoma 

分 类 号：R739.7[医药卫生—肿瘤]