Microbial spectrum and risk factors of endogenous endophthalmitis in a tertiary center of Northern China  

作　　者：Lin-Yang Gan Jun-Jie Ye Hui-Ying Zhou Han-Yi Min Lin Zheng 

机构地区：[1]Department of Ophthalmology,Peking Union MedicalCollege Hospital,Chinese Academy of Medical Sciences,Beijing 100730,China [2]Department of Ophthalmology,Beijing Tian Tan Hospital,Capital Medical University,Beijing 100730,China

出　　处：《International Journal of Ophthalmology(English edition)》2022年第10期1676-1682,共7页国际眼科杂志（英文版）

摘　　要：AIM: To study the clinical features, microbial spectrum, associated factors and prognosis of endogenous endophthalmitis(EE) in a group of Chinese patients.METHODS: The medical records from 32 eyes of 29 patients diagnosed with EE in Peking Union Medical College Hospital from January 2009 to October 2019 were reviewed. RESULTS: The initial visual acuity(VA) of 30 eyes in this study was worse than 20/400. Twenty-three eyes were diagnosed with fungal endophthalmitis and nine with bacterial endophthalmitis. The most common fungal and bacterial isolates were Candida and Klebsiella pneumoniae, respectively. Several rare fungi and bacteria species were also isolated from our patients, including Cryptococcus, Paecilomyces, Brucella, and Bacillus licheniformis. The leading risk factor for EE was diabetes. The most common extraocular infection locus was genitourinary tract. Vitrectomy was performed on twenty-nine eyes. Eight eyes achieved final VA of 20/400 or better. EE caused by Candida had a better prognosis.CONCLUSION: The visual outcome of EE is based on pathogens and prompt intervention. Early vitrectomy and antimicrobial treatment are beneficial for EE.

关 键 词：ENDOGENOUS ENDOPHTHALMITIS risk factors VITRECTOMY 

分 类 号：R77[医药卫生—眼科]