圆锥角膜合并K-F环1例并文献复习  

Keratoconus combined with Kayser-Fleischer ring:a case report and literature review

作　　者：王传玉 牟国营[1] WANG Chuanyu;MU Guoying(Department of Ophthalmology,Shandong Provincial Hospital,Cheeloo College of Medicine,Shandong University,Shandong Provincial Hospital Affiliated to Shandong First Medical University,Jinan 250021,Shandong,China;Cheeloo College of Medicine,Shandong University,Jinan 250012,Shandong,China)

机构地区：[1]山东大学附属省立医院/山东第一医科大学附属省立医院眼科,山东济南250021 [2]山东大学齐鲁医学院,山东济南250012

出　　处：《山东大学耳鼻喉眼学报》2022年第5期58-62,69,共6页Journal of Otolaryngology and Ophthalmology of Shandong University

摘　　要：圆锥角膜是一种以角膜变薄并向前锥形膨隆为特征的疾病。肝豆状核变性是一种先天性的肝铜代谢异常疾病,其特征性眼征为角膜Kayser-Fleischer环(K-F环)。研究发现,在多种先天性疾病中可合并圆锥角膜,但并不包括肝豆状核变性。论文报道1例圆锥角膜合并K-F环罕见病例,提示圆锥角膜与肝豆状核变性两种疾病间可能存在一定的联系。Keratoconus(KC) is a disease characterized by corneal thinning and ectasia.Hepatolenticular disease is an inherited disorder that primarily affects hepatic copper deposition with the characteristic ocular sign of Kayser-Fleischer ring(K-F ring).KC is considered to be associated with multiple diseases but not with hepatolenticular degeneration.Here,we present a very rare case of keratoconus with Kayser-Fleischer ring,suggesting that there may be a potential relationship between the two diseases.

关 键 词：圆锥角膜 Kayser-Fleischer环 肝豆状核变性 角膜交联术 

分 类 号：R772.23[医药卫生—眼科]