白血病颅内浸润的MRI分析  

MRI analysis of intracranial infiltration of leukemia

作　　者：张洪涛 蔡剑鸣 张召学 唐代迪 高珅 周娟 田宁 盛复庚 ZHANG Hong-tao;CAI Jian-ming;ZHANG Zhao-xue;TANG Dai-di;GAO Shen;ZHOU Juan;TIAN Ning;SHENG Fu-geng(Department of Radiology,the Fifth Medical Center,Chinese PLA General Hospital,Beijing 100071,China)

机构地区：[1]解放军总医院第五医学中心放射诊断科,北京100071

出　　处：《军事医学》2022年第8期606-609,共4页Military Medical Sciences

摘　　要：目的分析白血病颅内浸润的磁共振成像(MRI)影像表现,提高对白血病颅内浸润的认识及诊断水平。方法回顾性分析解放军总医院第五医学中心2009年2月至2019年12月确诊的22例白血病颅内浸润患者的临床资料和MRI征象,比较病变的部位、累及范围、T2WI、T1WI、DWI的信号特点及增强表现。结果白血病颅内浸润MRI表现为脑膜浸润和脑实质浸润。白血病脑膜浸润共13例,其表现分为4型:弥漫性硬脑膜增厚型,4例;弥漫性硬脑膜增厚伴局部结节型,5例;硬脑膜结节型,2例;软脑膜增厚型,2例。白血病脑实质浸润9例,其表现分为2型:脑内多发结节型,4例;脑内单发结节型,5例。脑实质浸润结节多表现为T2WI呈等、稍高信号,T1WI呈等、低信号,DWI多呈高信号,增强扫描中度到明显强化,病灶周围有不同程度脑水肿。结论白血病颅内浸润MRI表现有一定的特点,分为脑膜和脑实质浸润,MRI对病变的发现、诊断具有重要价值。Objective To analyze the magnetic resonance imaging(MRI)findings of intracranial infiltration of leukemia in order to advance our understanding and diagnosis of intracranial infiltration of leukemia.Methods The clinical data and MRI findings on 22 patients with leukemia with intracranial infiltration diagnosed in our hospital between February 2009 and December 2019 were analyzed retrospectively.The locations of lesions,extent of involvement,signal characteristics and enhancement features of T2WI,T1WI and DWI were compared and analyzed.Results Intracranial infiltration of leukemia manifested itself as meningeal infiltration and brain parenchyma infiltration on MRI.The manifestations of meningeal infiltration in 13 cases of leukemia fell into four types:the diffuse dural thickening type(n=4),diffuse dural thickening with local nodule type(n=5),dural nodular type(n=2)and leptomeningeal thickening type(n=2).There were 9 cases of cerebral parenchyma infiltration of leukemia,which were divided into two types:the multiple nodular type(n=4)and single nodular type(n=5).Most of the brain parenchyma infiltrating nodules showed iso-and slightly high-signals on T2WI,iso-and low-signals on T1WI,high-signals on DWI,moderate to obvious enhancement on contrast-enhanced scan,and different degrees of brain edema around the focus.Conclusion MRI findings of intracranial infiltration of leukemia have some characteristics,which can be divided into meningeal and cerebral parenchyma infiltration.MRI is of great value in the detection and diagnosis of lesions.

关 键 词：白血病 颅内浸润 磁共振成像 

分 类 号：R733.7[医药卫生—肿瘤]