模拟过氧化微环境中的钛表面特性及其腐蚀行为研究  

Study of surface property and corrosion behavior of pure titanium in a simulated peroxidation microenvironment

作　　者：高红媛 周以恒[1] 邱憬 GAO Hongyuan;ZHOU Yiheng;QIU Jing(Department of Oral Implantology,Affiliated Stomatological Hospital of Nanjing Medical University,Jiangsu Province Key Laboratory of Oral Diseases,Jiangsu Privince Engineering Research Center of Stomatological Trarslational Medicine,Nanjing 210029;Department of Prosthodontics,Taizhou Stomatological Hospital,Taizhou 225300,China)

机构地区：[1]南京医科大学附属口腔医院种植科,江苏省口腔疾病研究重点实验室,江苏省口腔转化医学工程研究中心,江苏南京210029 [2]泰州市口腔医院修复科,江苏泰州225300

出　　处：《南京医科大学学报（自然科学版）》2022年第10期1394-1401,共8页Journal of Nanjing Medical University(Natural Sciences)

基　　金：国家自然科学基金(81870799);江苏省重点研发计划(社会发展)项目(BE2019728);江苏高校优势学科建设工程资助项目(2018-87)。

摘　　要：目的:研究模拟过氧化微环境对钛表面特性及其腐蚀行为的影响。方法:将纯钛试件浸泡于不同模拟体液中,分为Hanks’平衡盐溶液(HBSS)组、HBSS+牛血清白蛋白(BSA)组、HBSS+过氧化氢(H_(2)O_(2))组、HBSS+BSA+H_(2)O_(2)组。收集浸泡7 d后的试件及浸提液,采用扫描电镜(scanning electron microscopy,SEM)、X射线光电子能谱仪(X-ray photoelectron spectroscopy,XPS)分析钛表面特性;采用电化学工作站检测不同模拟体液中纯钛试件的腐蚀行为;采用电感耦合等离子体发射光谱仪(inductively coupled plasma optical emission spectrometer,ICP-OES)检测各组浸提液中的钛离子释放量。结果:SEM和XPS分析结果显示,HBSS+H_(2)O_(2)组钛表面微形貌变化明显,钛和氧元素含量显著升高,其余各组无明显差异。电化学测试获得的奈奎斯特图(Nyquist)、波特阻抗图、波特相位图以及等效电路拟合数据显示,HBSS+H_(2)O_(2)组钛表面氧化膜的腐蚀阻抗最小,HBSS+BSA+H_(2)O_(2)组次之,HBSS+BSA组和HBSS组最高。ICP-OES检测发现,HBSS+H_(2)O_(2)组的钛离子释放量较其余各组显著增加。结论:模拟过氧化微环境中H_(2)O_(2)会破坏钛表面氧化膜,加剧钛腐蚀行为,引发钛离子释放,而BSA和H_(2)O_(2)共同作用时,BSA可抑制H_(2)O_(2)对钛表面的腐蚀。Objective:To study the effects of surface property and corrosion behavior of pure titanium in a simulated peroxidation microenvironment.Methods:The pure titanium specimens were immersed in different simulated body fluids and divided into Hanks’balanced salt solution(HBSS)group,HBSS+bovine serum albumin(BSA)group,HBSS+hydrogen peroxide(H_(2)O_(2))group and HBSS+BSA+H_(2)O_(2)group.The test samples and soaking solutions after 7 days of immersion were collected,and the titanium surface properties were analyzed by scanning electron microscopy(SEM)and X-ray photoelectron spectroscopy(XPS).An electrochemical potentiostat was used to investigate the corrosion behaviors of pure titanium specimens in different simulated body fluids.The quantities of titanium ion release in soaking solutions of different groups were detected by inductively coupled plasma optical emission spectrometer(ICPOES).Results:SEM and XPS analysis results demonstrated that the micro-morphology of titanium surface in HBSS+H_(2)O_(2)group changed obviously with significant increases in the contents of titanium and oxygen,whereas there were no remarkable differences in other groups.The Nyquist plots,Bode|Z|diagrams,Bode-phase diagrams and equivalent circuit fitting data obtained by electrochemical test showed that the corrosion resistance of titanium surface oxide film in HBSS+H_(2)O_(2)group was the lowest,followed by HBSS+BSA+H_(2)O_(2)group,and HBSS+BSA group and HBSS group were the highest.ICP-OES revealed that the release of titanium ions in HBSS+H_(2)O_(2)group was significantly higher than those in other groups.Conclusion:In the simulated peroxidation microenvironment,H_(2)O_(2)could destroy the oxide film on titanium surface,aggravate the corrosion behavior of titanium and trigger the release of titanium ions.When BSA and H_(2)O_(2)act together,BSA could inhibit the corrosion of titanium surface by H_(2)O_(2).

关 键 词：钛 腐蚀 过氧化氢 牛血清白蛋白 

分 类 号：R783.1[医药卫生—口腔医学]