基于数据挖掘对古中医文献治疗脑卒中的用药规律研究  

A study on the medication rules for stroke in ancient TCM medicine literature based on data mining

作　　者：莫凌丽 辛振刚[2] 周元成[2] 赵一宇[2] 杨柯[1] MO Lingli

机构地区：[1]广西中医药大学,广西南宁530200 [2]钦州市第二人民医院,广西钦州535099

出　　处：《中医临床研究》2022年第29期80-84,共5页Clinical Journal Of Chinese Medicine

基　　金：广西研究生教育创新计划项目(YCSW2020182);钦州市科学研究与技术开发计划项目(201820202)。

摘　　要：目的:挖掘古中医文献治疗脑卒中的组方用药规律。方法:以方书类文献《中华医典》为资料来源,使用Excel、SPSS Modeler、SPSS Statistics软件对纳入处方进行中药频次、关联规则、系统聚类分析。结果:在纳入的557首方剂中,单药防风最为常用,药物四气以温、平为主,五味中辛、甘味为主,归经中肝经、心经居多,使用最多的药物类别为发散风寒药、息风止痉药。关联规则分析中发现强链药对216对,关联规则54种,系统聚类分析归为8大类。结论:古文献治疗脑卒中的处方以祛风通络药物为主,补虚、清热、豁痰等药物也因不同证型相互配伍。Objective:To explore the medication rules for stroke in ancient TCM medicine literature.Methods:Excel,SPSS Modeler and SPSS Statistics were used to analyze the frequency,association rule and systematic cluster of TCM medicines in the included literature.Results:Among the included 557 prescriptions,Fangfeng(Radix Saposhnikoviae)was the most commonly used,the medicinal properties were mainly warm and mild,the medicinal flavors were mainly pungent and sweet,and most of them flowed into the liver meridian and heart meridian.The most commonly used medicines were dispersing wind-cold medicine,and wind-suppressing and antispasmodic medicine.A total of 216 strong chain medicine-pairs were found in the association rule analysis,with 54 kinds of association rule;and 8 categories were classified in the systematic cluster analysis.Conclusion:The prescriptions on stroke in ancient TCM literature are mainly used for expelling wind and dredging collaterals,and the medicines of tonifying deficiency,clearing away heat,and removing phlegm are also compatible with each other according to different syndromes.

关 键 词：脑卒中 用药规律 数据挖掘 中药组方 

分 类 号：R743.33[医药卫生—神经病学与精神病学]