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作 者:许林[1] Xu Lin(Department of Thoracic Surgery,Jiangsu Cancer Hospital,Nanjing 210009,China)
出 处:《中华胸部外科电子杂志》2022年第3期168-172,共5页CHINESE JOURNAL OF THORACIC SURGERY:Electronic Edition
摘 要:肺上沟瘤(Pancoast瘤)的广义概念是肺尖部的任何病变(原发性恶性肿瘤、转移肿瘤、良性肿瘤等)压迫或侵犯了C8、T1神经根、交感神经链、星状神经节,而产生Pancoast综合征。肺上沟瘤的狭义概念特指原发在肺尖部的支气管肺癌,其是非小细胞肺癌(NSCLC)的一种少见的临床亚型,经常侵犯肋骨、锁骨下血管、神经等胸廓入口结构。狭义的肺上沟瘤是本文主要的研究对象。肺上沟瘤从最初的无法治疗,发展到现在的放疗、化疗和手术的多学科治疗,治疗效果有了显著提升。近几十年来,肺上沟瘤的手术路径、手术方式也在不断迭代中,外科治疗方式的进展显著改善了肺上沟瘤患者的长期生存。本文就肺上沟瘤的治疗,特别是外科治疗的进展进行述评,为肺上沟瘤的治疗提供较为全面的参考。Superior sulcus tumor is considered as any lesion,including primary malignant tumor,metastatic tumor,benign tumor,etc.,typically invading the C8 or T1 nerve roots,sympathetic nerve chain and stellate ganglion.A distinct clinical presentation now commonly referred to as Pancoast syndrome,which is classified as a relatively rare clinical subtype of non-small cell lung cancer(NSCLC),and the thoracic inlet such as ribs,subclavian vessels,and nerves could also be invaded.From untreatable to the present multidisciplinary treatments of radiotherapy,chemotherapy and surgery,the therapeutic effect has been significantly improved.In recent decades,surgical approaches have been advanced,which has significantly improved the long-term survival of patients with superior sulcus tumors.This article reviews the treatment of superior sulcus tumor,especially the progress of surgical treatment,and provides a more comprehensive reference for clinical treatment of superior sulcus tumor.
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