β-环糊精的低临界溶解温度现象及其在有序纳米孔道片晶制备中的应用  

Low Critical Dissolution Temperature Behavior ofβ-Cyclodextrin and Its Application in the Preparation ofβ-Cyclodextrin Sheet Crystal with Ordered Nano-channel

作　　者：谭乐见 仲宣树 王锦[2] 刘宗建 张爱英[1] 叶霖[1] 冯增国[1] TAN Lejian;ZHONG Xuanshu;WANG Jin;LIU Zongjian;ZHANG Aiying;YE Lin;FENG Zengguo(School of Materials Science and Engineering,Beijing Institute of Technology,Beijing 100081,China;Key Laboratory of Multifunctional Nanomaterials and Smart Systems,Suzhou Institute of Nano-Tech and Bionics,Chinese Academy of Sciences,Suzhou 215123,China;Beijing Rehabilitation Hospital,Capital Medical University,Beijing 101144,China)

机构地区：[1]北京理工大学材料学院,北京100081 [2]中国科学院苏州纳米技术与纳米仿生研究所,纳米轻量化重点实验室,苏州215123 [3]首都医科大学附属北京康复医院,北京101144

出　　处：《高等学校化学学报》2022年第11期198-204,共7页Chemical Journal of Chinese Universities

基　　金：苏州市科技局基础研究试点项目(批准号:SJC2021008)资助。

摘　　要：将β-环糊精(β-CD)溶解于N,N-二甲基甲酰胺(DMF)中,加热至140℃后有大量白色晶体析出.扫描电子显微镜观察发现析出物为β-CD片状结晶.红外光谱(IR)和核磁共振波谱(NMR)结果证明了片状结晶的化学结构与β-CD原料相同.热重分析(TGA)和差示扫描量热(DSC)分析结果证明片状结晶的理化性质与β-CD原料相同.X射线衍射分析(XRD)测试结果表明,β-CD片晶的结晶结构与β-CD原料不同.利用Diamond软件模拟了具有开通管道结晶结构的β-CD晶体的XRD谱图,发现其与实测的β-CD片晶谱图基本相符,说明β-CD片晶具有有序纳米开通管道结晶结构.比表面积测试和酚酞吸附实验进一步证实β-CD片晶具有比β-CD原料更大的比表面积和更好的吸附性能.In this paper,β-cyclodextrin(β-CD)was dissolved in N,N-dimethylformamide solution(DMF),and a large number of white crystals were precipitated after the solution was heated to 140℃.It was found that the precipitated crystals wereβ-CD sheet crystals by scanning electron microscopy(SEM)as well as infrared Spectroscopy(IR)and Nuclear magnetic resonance(NMR).Thermogravimetric analysis(TGA)and differential scanning calorimetry(DSC)analysis showed that the sheet crystals had the same physical and chemical properties asβ-CD raw materials.The X-rays diffraction(XRD)results showed thatβ-CD sheet had different crystalline structure fromβ-CD raw materials.The XRD patterns ofβ-CD crystal with open-chanel crystalline structure were simulated by Diamond software,which is consistent with that ofβ-CD sheet,indicating thatβ-CD sheet has ordered open-channel crystalline structure.Brunauer-Emmett-Tellern(BET)measurement and phenolphthalein adsorption experiment further confirmed thatβ-CD sheet had larger specific surface area and better adsorption performance thanβ-CD raw materials.

关 键 词：Β-环糊精 低临界溶解温度 管道结晶结构 片状晶体 吸附 

分 类 号：O631.2[理学—高分子化学]