细针穿刺联合细胞块技术在涎腺黏液表皮样癌诊断中的应用  

Application of fine needle aspiration combined with cell block technique in the diagnosis of mucoepidermoid carcinoma of salivary gland

作　　者：杨艳[1] 余小蒙[1] 王苗 张长河[1] YANG Yan;YU Xiao-meng;WANG Miao;ZHANG Chang-he(Department of Pathology,Beijing Friendship Hospital,Capital Medical University,Beijing 100050,China)

机构地区：[1]首都医科大学附属北京友谊医院病理科,北京100050

出　　处：《北京口腔医学》2022年第5期350-353,共4页Beijing Journal of Stomatology

摘　　要：目的探讨细针穿刺联合细胞块技术在涎腺黏液表皮样癌诊断中的应用价值。方法回顾近10年诊断为涎腺黏液表皮样癌和可疑黏液表皮样癌的52例病例,并随访其术后病理结果,其中43例同时制作细胞块并行HE、AB-PAS及免疫组化染色。结果单纯FNA诊断黏液表皮样癌的确诊率为11.1%(1/9),FNA联合细胞块及免疫组化的确诊率为46.5%(20/43),细胞学总确诊率40.4%(21/52例)。细胞学确诊病例与术后组织学诊断符合率为100%(21/21),细胞学可疑病例与术后组织学诊断符合率为83.9%(26/31)。细胞学与组织学总符合率90.4%(47/52)。结论FNA联合细胞块技术是提高涎腺黏液表皮样癌术前确诊率的重要手段,对临床制订合理的诊疗方案有参考意义。Objective To investigate the value of fine needle aspiration combined with cell block technique in the diagnosis of mucoepidermoid carcinoma of salivary gland.Methods Fifty-two cases of mucoepidermoid carcinoma were retrospectively reviewed.Cell blocks were made in 43 cases and stained with HE,AB-PAS and immunohistochemistry.Results The diagnosis rate of mucoepidermoid carcinoma by FNA alone was 11.1%(1/9),and the diagnosis rate of FNA combined with cell block and immunohistochemistry was 46.5%(20/43).The total diagnostic rate of cytology was 40.4%(21/52 cases).The coincidence rate between cytological confirmed cases and postoperative histological diagnosis was 100%(21/21),and the coincidence rate between cytological suspected cases and postoperative histological diagnosis was 83.9%(26/31).The total coincidence rate of cytology and histology was 90.4%(47/52).Conclusions FNA combined with cell block technology is an important means to improve the preoperative diagnosis rate of mucoepidermoid carcinoma of salivary gland.

关 键 词：细针穿刺 细胞块技术 涎腺 黏液表皮样癌 

分 类 号：R739.8[医药卫生—肿瘤]