Recent advancements in noninvasive brain modulation for individuals with autism spectrum disorder  

作　　者：Jessica R.Griff Jake Langlie Nathalie B.Bencie Zachary J.Cromar Jeenu Mittal Idil Memis Steven Wallace Alexander E.Marcillo Rahul Mittal Adrien A.Eshraghi 

机构地区：[1]Hearing Research and Communication Disorders Laboratory,Department of Otolaryngology,Neurotology Division,University of Miami Miller School of Medicine,Miami,FL,USA [2]Department of Neurological Surgery,University of Miami Miller School of Medicine,Miami,FL,USA [3]Department of Biomedical Engineering,University of Miami,Coral Gables,FL,USA [4]Department of Pediatrics,University of Miami Miller School of Medicine,Miami,FL,USA

出　　处：《Neural Regeneration Research》2023年第6期1191-1195,共5页中国神经再生研究（英文版）

基　　金：supported by translational grant from the HERA Foundation(to AAE).

摘　　要：Autism spectrum disorder is classified as a spectrum of neurodevelopmental disorders with an unknown definitive etiology.Individuals with autism spectrum disorder show deficits in a variety of areas including cognition,memory,attention,emotion recognition,and social skills.With no definitive treatment or cure,the main interventions for individuals with autism spectrum disorder are based on behavioral modulations.Recently,noninvasive brain modulation techniques including repetitive transcranial magnetic stimulation,intermittent theta burst stimulation,continuous theta burst stimulation,and transcranial direct current stimulation have been studied for their therapeutic properties of modifying neuroplasticity,particularly in individuals with autism spectrum disorder.Preliminary evidence from small cohort studies,pilot studies,and clinical trials suggests that the various noninvasive brain stimulation techniques have therapeutic benefits for treating both behavioral and cognitive manifestations of autism spectrum disorder.However,little data is available for quantifying the clinical significance of these findings as well as the long-term outcomes of individuals with autism spectrum disorder who underwent transcranial stimulation.The objective of this review is to highlight the most recent advancements in the application of noninvasive brain modulation technology in individuals with autism spectrum disorder.

关 键 词：autism spectrum disorder behavior COGNITION neurostimulation interventions noninvasive brain modulation theta burst stimulation transcranial direct current stimulation transcranial magnetic stimulation 

分 类 号：R749.94[医药卫生—神经病学与精神病学]