Ketamine,a trauma analgesic with sex-specific immunomodulatory function  

作　　者：Haley F.Spencer Rina Y.Berman Martin Boese Kwang H.Choi 

机构地区：[1]Program in Neuroscience,Uniformed Services University,Bethesda,MD,USA [2]Center for the Study of Traumatic Stress,Uniformed Services University,Bethesda,MD,USA [3]Daniel K.Inouye Graduate School of Nursing,Uniformed Services University,Bethesda,MD,USA [4]Department of Psychiatry,F.E.Hébert School of Medicine,Uniformed Services University,Bethesda,MD,USA

出　　处：《Neural Regeneration Research》2023年第6期1263-1264,共2页中国神经再生研究（英文版）

摘　　要：Ketamine,a multimodal dissociative anesthetic,produces powerful analgesia at subanesthetic doses in traumatically injured patients.As ketamine does not induce respiratory depression or hemodynamic instability,the Committee on Tactical Combat Casualty Care for the US military recommends the use of subanesthetic doses of ketamine for acute pain management(Butler et al.,2014).Additionally,ketamine may have immunomodulatory effects after injury at subanesthetic doses,mediating the balance of pro-and anti-inflammatory processes(Loix et al.,2011;De Kock et al.,2013).

关 键 词：doses ACUTE 

分 类 号：R741[医药卫生—神经病学与精神病学]