小脑发育不良性神经节细胞瘤的多模态磁共振诊断  

Multimodality MRI Diagnosis of Cerebellar Dysplastic Ganglioma

作　　者：何荣华 苏航 张坤[2] 许凯 王艳 任转勤 田宏哲[2] 张明[1] HE Rong-hua;SU Hang;ZHANG Kun;XU Kai;WANG Yan;REN Zhuan-qin;TIAN Hong-zhe;ZHANG Ming(Department of Medical Imaging,The First Affiliated Hospital of Xi'an Jiaotong University,Xi'an 710061,Shaanxi Province,China;Department of Medical Imaging,Baoji Central Hospital,Baoji 721008,Shaanxi Province,China)

机构地区：[1]西安交通大学第一附属医院医学影像科,陕西西安710061 [2]陕西省宝鸡市中心医院医学影像科,陕西宝鸡721008

出　　处：《中国CT和MRI杂志》2022年第11期1-3,共3页Chinese Journal of CT and MRI

基　　金：陕西省卫健委项目(2018C001)。

摘　　要：目的探讨小脑发育不良性神经节细胞瘤的多模态MRI成像特征,为临床和影像诊断工作提供经验。方法回顾性分析我院收治的1例小脑发育不良性神经节细胞瘤患者资料,包括临床体征、影像检查及病理报告、治疗措施等,并复习相关文献报道,讨论其多模态MRI成像特征。结果MRI平扫见“虎纹”征,DWI信号略增高,DTI示病变区FA值较对侧减低,周围白质纤维束受压移位,ESWAN见病变区有增多小静脉血管,3D ASL(PLD=2.0s)病变区灌注增高,增强扫描病变无强化、其内见多发细小血管影,MRS见病变内NAA略减低,Cho/Cr无增高。随后患者行左侧小脑半球肿瘤部分切除术,病理结果为小脑发育不良性神经节细胞瘤(WHOI级)。结论小脑发育不良性神经节细胞瘤属于神经元和混合性神经元-胶质瘤,是一种罕见的小脑良性肿瘤,多模态MRI成像对该病的术前诊断和深入的影像-病理特征研究有重要意义。Objective Investigate the multimodal MRI imaging characteristics of dysplastic cerebellar gangliocytomas,in order to provide experience for clinical and imaging diagnosis.Methods A case of dysplastic cerebellar gangliocytoma admitted to our hospital was retrospectively analyzed,including clinical signs,imaging examination,pathological report,treatment measures,etc.What’s more,we reviewed relevant literature reports to discuss the features of multimodal MRI imaging.Results MRI showed"tiger stripe sign",and DWI was slightly increased,DTI showed that the FA value in the lesion area was reduced compared with the contralateral side,and the surrounding white matter fiber tracts were shifted under pressure.ESWAN showed that there were more small veins in the lesion area.3D ASL(PLD=2.0s)showed increased perfusion in the lesion area.MRS showed a slight decrease in NAA and no increase in Cho/Cr.Subsequently,the patient underwent partial left cerebellar hemisphere tumor resection,and the pathological result was dysplastic cerebellar gangliocytoma(WHOI grade).Conclusion Dysplastic cerebellar gangliocytoma belongs to neuronal and mixed neuronal glioma,which is a rare benign cerebellar tumor.Multimodal MRI imaging is of great significance for preoperative diagnosis and in-depth imaging and pathological features of this disease.

关 键 词：神经元和混合性神经元-胶质瘤 小脑发育不良性神经节细胞瘤 多模态 磁共振成像 

分 类 号：R739.41[医药卫生—肿瘤] R445.2[医药卫生—临床医学]